nutrients-logo

Journal Browser

Journal Browser

Effects of Diet on Muscle Mass in Older Adults

A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Geriatric Nutrition".

Deadline for manuscript submissions: closed (25 April 2023) | Viewed by 7681

Special Issue Editor

Department of Nutrition and Gerontology, German Institute of Human Nutrition, Potsdam-Rehbrücke, Nuthetal, Germany
Interests: nutrition in old age; gerontology; sarcopenia; muscle function in old age; cachexia and malnutrition; body composition; postprandial response in old age; inflammaging
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Aging is associated with changes in body composition, such as a loss of muscle mass and increase in body fat. This is frequently accompanied by a progressive decline in physical performance, which, in turn, increases the risk of physical disability and need of care. Ultimately, quality of life is reduced and health care burden is increased. In the context of demographic changes, preserving muscle mass and function is, therefore, not only of individual but of societal relevance.

Although underlying mechanisms are still not fully understood, they are multi-factorial and involve both age-related processes and lifestyle factors. Nutrition most likely plays a central role in both prevention and treatment of loss of muscle mass. Therefore, this Special Issue “Effects of Diet on Muscle Mass in Older Adults” invites original research and reviews exploring the relationship of nutrition and muscle mass and function in the old.

Prof. Dr. Kristina Norman
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Nutrients is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • diet
  • muscle mass
  • muscle strength
  • aging
  • inflammation
  • protein

Published Papers (2 papers)

Order results
Result details
Select all
Export citation of selected articles as:

Research

11 pages, 807 KiB  
Article
Efficacy and Safety of 6-Month High Dietary Protein Intake in Hospitalized Adults Aged 75 or Older at Nutritional Risk: An Exploratory, Randomized, Controlled Study
by Shota Moyama, Yuichiro Yamada, Noboru Makabe, Hiroki Fujita, Atsushi Araki, Atsushi Suzuki, Yusuke Seino, Kenichiro Shide, Kyoko Kimura, Kenta Murotani, Hiroto Honda, Mariko Kobayashi, Satoshi Fujita, Koichiro Yasuda, Akira Kuroe, Katsushi Tsukiyama, Yutaka Seino and Daisuke Yabe
Nutrients 2023, 15(9), 2024; https://doi.org/10.3390/nu15092024 - 22 Apr 2023
Viewed by 2962
Abstract
The aim of this study was to investigate the effects of increased dietary protein in daily-life settings in Japan for 6 months on the activities of daily living (ADL) in adults aged 75 or older at nutritional risk. The study was an open-label, [...] Read more.
The aim of this study was to investigate the effects of increased dietary protein in daily-life settings in Japan for 6 months on the activities of daily living (ADL) in adults aged 75 or older at nutritional risk. The study was an open-label, exploratory, randomized controlled trial conducted at seven hospitals in Japan. The study participants were adults aged 75 or older who were hospitalized for treatable cancer, pneumonia, fractures, and/or urinary-tract infection at nutritional risk. The primary outcome was change in grip strength, skeletal muscle, and ADL indices (Barthel index, Lawton score). One hundred sixty-nine patients were randomly assigned to the intensive care (IC) or standard care (SC) group; the protein intake goals (g/kgw/day) were 1.5 for IC and 1.0 for SC. There was a significant improvement in grip strength only in the IC group (1.1 kg: 95% CI 0.1 to 2.1) (p = 0.02). While the skeletal muscle index and ADL indices were not significantly improved in either group, the improvement ratio tended to be greater in the IC group. There was no decrease in renal function in either group. Thus, intervention of increased dietary protein in daily-life settings for 6 months in adults aged 75 or older with treatable cancer, pneumonia, fractures, and/or urinary-tract infection and at nutritional risk may be effective in ameliorating loss of muscle strength. Full article
(This article belongs to the Special Issue Effects of Diet on Muscle Mass in Older Adults)
Show Figures

Figure 1

12 pages, 293 KiB  
Article
Effects of an Omega-3 Supplemented, High-Protein Diet in Combination with Vibration and Resistance Exercise on Muscle Power and Inflammation in Old Adults: A Pilot Randomized Controlled Trial
by Ulrike Haß, Bastian Kochlik, Catrin Herpich, Stefan Rudloff and Kristina Norman
Nutrients 2022, 14(20), 4274; https://doi.org/10.3390/nu14204274 - 13 Oct 2022
Cited by 7 | Viewed by 4384
Abstract
Background: Inflammaging is considered to drive loss of muscle function. Omega-3 fatty acids exhibit anti-inflammatory properties. Therefore, we examined the effects of eight weeks of vibration and home-based resistance exercise combined with a whey-enriched, omega-3-supplemented diet on muscle power, inflammation and muscle biomarkers [...] Read more.
Background: Inflammaging is considered to drive loss of muscle function. Omega-3 fatty acids exhibit anti-inflammatory properties. Therefore, we examined the effects of eight weeks of vibration and home-based resistance exercise combined with a whey-enriched, omega-3-supplemented diet on muscle power, inflammation and muscle biomarkers in community-dwelling old adults. Methods: Participants were randomized to either exercise (3x/week, n = 20), exercise + high-protein diet (1.2–1.5 g/kg, n = 20), or exercise + high-protein and omega-3-enriched diet (2.2 g/day, n = 21). Muscle power (watt/m2) and chair rise test (CRT) time (s) were assessed via CRT measured with mechanography. Furthermore, leg strength (kg/m2) and fasting concentrations of inflammatory (interleukin (IL-) 6, IL-10, high-mobility group box-1 (HMGB-1)) and muscle biomarkers (insulin-like growth factor (IGF-) 1, IGF-binding protein-3, myostatin) were assessed. Results: Sixty-one participants (70.6 ± 4.7 years; 47% men) completed the study. According to generalized linear mixed models, a high-protein diet improved leg strength and CRT time. Only IGF-1 increased with additional omega-3. Sex-specific analyses revealed that muscle power, IL-6, IL-6/IL-10 ratio, and HMGB-1 improved significantly in the male high-protein, omega-3-enriched group only. Conclusion: Vibration and home-based resistance exercise combined with a high-protein, omega-3-enriched diet increased muscle power and reduced inflammation in old men, but not in old women. While muscle biomarkers remained unchanged, a high-protein diet combined with exercise improved leg strength and CRT time. Full article
(This article belongs to the Special Issue Effects of Diet on Muscle Mass in Older Adults)
Show Figures

Graphical abstract

Back to TopTop