Therapeutic and Clinical Applications of Omega‑3 Polyunsaturated Fatty Acid Dietary Supplementation
A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Lipids".
Deadline for manuscript submissions: 25 September 2026 | Viewed by 122
Special Issue Editors
Interests: fatty acid metabolism; elongation and desaturarion of polyunsaturated fatty acids (PUFAs); n-3 PUFAs in diet and health; fatty acid and oxidative stress; fatty acid and inflammatory response; fatty acid in health or disease
Special Issues, Collections and Topics in MDPI journals
Interests: fatty acid and microbiota; fatty acids and intestinal inflamatorie response; dietary fatty acid and gastro—intestinal diseases; dietary fats and insulin resistance; dietary fats; diabetes type I and II
Special Issue Information
Dear Colleagues,
Omega-3 or n-3 polyunsaturated fatty acids (n-3 PUFAs) are a family of nutrients with essential and relevant functions for humans, from reproduction and embryonic development to aging. Among the n-3 PUFAs, alpha-linolenic acid (C18:3n-3, ALA), eicosapentaenoic acid (C20:4n-3, EPA), and docosahexaenoic acid (C22:6n-3, DHA) have been shown to have the most physiological functions and clinical applications. In this regard, growing clinical evidence has demonstrated that dietary supplementation with n-3 PUFAs provides significant benefits for individuals, particularly in neurological, cardiovascular systems, and in different clinical situations such as metabolic syndrome, specific types of cancer, or inflammatory and reproductive disturbances, among others. Regarding the progress or advances in therapeutic and clinical applications of n-3 PUFAs through the use of nutritional supplements, it is relevant to mention that technological advances have allowed the development of n-3 PUFA nutritional supplements with a high concentration of these fatty acids (particularly EPA and/or DHA) with excellent quality (stable to oxidation and certified as contaminant-free).
Considering this background, the purpose of this Special Issue is to present updated evidence of the health benefits of n-3 PUFAs dietary supplementation in clinical trials, considering different therapeutic or clinical applications, such as: pregnancy and breast feeding period, metabolic and cardiovascular health, inflammation and pain, different types of cancer, cognitive impairment and neurodegenerative diseases or critical patients.
Finally, we hope that this Special Issue will become a source of updated scientific evidence on the therapeutic role and clinical applications of Omega-3 Polyunsaturated Fatty acid dietary supplementation in humans.
Dr. Rodrigo Valenzuela
Guest Editor
Dr. Lissette Duarte
Dr. Yasna Muñoz
Guest Editor Assistants
Manuscript Submission Information
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Keywords
- Omega-3 or n-3 PUFAs
- dietary supplementation
- nutrition
- health
- clinical situacionts
- prevention
- treatment
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