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Epidemiological Epigenomics on Nutrition and Health

A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Nutrigenetics and Nutrigenomics".

Deadline for manuscript submissions: 25 August 2024 | Viewed by 91

Special Issue Editor

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Guest Editor
Director of Epigenomics in Endocrinology and Nutrition Group, Health Research Institute of Santiago de Compostela (IDIS), Santiago de Compostela, Spain
Interests: epigenomics; nutriepigenomics; mitoepigenetics; DNA methylation; epigenetic clock; nutrition; atlantic diet; ketogenic diet; ketone bodies; bioactive compounds; vitamins; antioxidants; cancer; obesity; oxidative stress; inflammation; adipokines; myokines; hepatokines; body composition; metabolism; biomarkers; liquid biopsia; adipose tissue; liver; muscle; blood leukocytes
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Special Issue Information

Dear Colleagues,

Human health is strongly determined by environmental factors such as dietary patterns, foods, nutrients, pollutants, toxics, or social stress, besides genetics. It is well established that the molecular mechanisms by means of which environmental factors alter biological processes are epigenetic mechanisms. These epigenetic mechanisms include DNA methylation marks, histone modifications, non-coding RNA (microRNA, long non-coding RNA) and sirtuin expression, epigenetic clock, mitochondrial DNA methylation, and telomere length. Epigenetics play a relevant role in physiological and pathological conditions by regulating gene expression. In this context, there has been growing interest in studying the associations between epigenetic variations and disease susceptibility. However, the elucidation of epigenetic biomarkers and the characterization of epigenetic therapeutic targets are still limited, which make the epidemiological epigenetics an emerging and fruitful field in clinical settings.

The purpose of this Special Issue is to add to the research which uses epigenetics only or in combination with other omic-technologies (genetics, transcriptomics, metabolomics, and microbiomics) in the identification of biomarkers of disease and exposure, or of susceptible populations, as well as in the characterization of modulators of epigenetic mechanisms. This could help to design methods for the prevention and treatment of non-communicable diseases such as obesity, diabetes, cardiovascular disease, fatty liver disease, neurological disorders, and cancer, and promote healthy aging.

Submissions may include population-based studies of variation in epigenetic marks, as well as studies regarding the effects of specific diets, dietary patterns, foods, nutrients, bioactive compounds, endocrine disruptors, or toxics (alcohol, tobacco, and abuse drugs) on changes in epigenomics parameters that could be associated with the biological responses and/or the risk of chronic non-communicable diseases and aging. The identification of epigenetic marks as biomarkers or drivers of disease could help to design more precise and personalized programs for disease prevention and management. This identification can be performed in body fluids (plasma, saliva, urine, and sperm) or tissues and at the nuclear or mitochondrial genome.

This Special Issue welcomes the submission of manuscripts describing original research or reviews of the scientific literature in humans (interventional, observational, or cohort studies).

I look forward to receiving your contributions.

Dr. Ana B. Crujeiras
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Nutrients is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • epigenetics
  • nutriepigenomics
  • mitoepigenetics
  • DNA methylation
  • microRNA
  • long non-coding RNA
  • inflammation
  • oxidative stress
  • dietary patterns
  • bioactive compounds
  • vitamins
  • antioxidants
  • disease
  • aging
  • longevity

Published Papers

This special issue is now open for submission.
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