Plant Bioactives and Their Derivatives: Implications for Gut Dysbiosis
A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Phytochemicals and Human Health".
Deadline for manuscript submissions: 15 August 2026 | Viewed by 182
Editors
Interests: medicinal plants; intestinal microflora; beneficial bacteria; microbial fermentation
Special Issue Information
Dear Colleagues,
Plant-based bioactive compounds have been extensively studied for their antioxidant, anti-inflammatory, and immunomodulatory properties, which contribute substantially to human health. Regular consumption of these compounds is associated with a reduced risk of chronic diseases, as they play a vital role in neutralizing free radicals and modulating metabolic pathways. Recent research has highlighted the capacity of plant-derived bioactive compounds to modulate the composition of gut microbiota and exert neuroprotective effects, underscoring their growing importance in preventive medicine and functional nutrition. A balanced gut microbial ecosystem supports metabolic homeostasis, whereas dysbiosis—characterized by alterations in microbial diversity and function—has been increasingly linked to inflammation, metabolic disorders, and neurodegenerative conditions. Beneficial gut bacteria play a pivotal role in the bioconversion of plant bioactives into more bioavailable and biologically active metabolites, thereby enhancing their intestinal absorption and systemic efficacy.
This Special Issue aims to explore the significance of plant-based bioactive compounds and their bioconverted derivatives in addressing gut dysbiosis. We welcome in vitro, experimental, and clinical studies, as well as comprehensive reviews, on these topics. Submissions may focus on the mechanisms by which plant bioactive compounds exert their beneficial effects, or may explore innovative bioconversion processes that are experimentally validated and clearly demonstrate improvements in bioavailability, efficacy, and human health-related outcomes.
Dr. Narandalai Danshiitsoodol
Dr. Masafumi Noda
Guest Editors
Manuscript Submission Information
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Keywords
- plant-based bioactive compounds
- herbal medicine
- beneficial bacteria
- prebiotics
- postbiotics
- SCFA
- bioconversion
- gut microflora
- anti-inflammation
- antioxidation
- anti-obesity
- dysbiosis
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