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Diet and Nutrition for Pediatric Asthma

A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Pediatric Nutrition".

Deadline for manuscript submissions: 25 August 2025 | Viewed by 610

Special Issue Editors


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Guest Editor
Department of Food, Nutrition and Dietetics, La Trobe University, Bundoora, VIC, Australia
Interests: pediatric asthma; nutrition; Mediterranean diet; vitamin D; omega-3 fatty acids; folate; metabolomics; epigenetics; exercise-induced asthma; respiratory health

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Guest Editor
Department of Experimental Physiology, Medical School, National and Kapodistrian University of Athens, 11527 Athens, Greece
Interests: epigenetics; pediatric asthma

Special Issue Information

Dear Colleagues,

Secular trends show that asthma is one of the most common chronic diseases in childhood, ranking 20th among the top conditions worldwide for disability-adjusted years. In daily clinical practice, pediatric asthma constitutes a complex and multifaceted challenge that contributes significantly to the global burden of respiratory diseases in children. It is believed that the intricate interplay between genetic, environmental, and lifestyle factors including diet is implicated in asthma development. Understanding how dietary factors can influence the immunological mechanisms underlying this condition and their potential role in predisposing children to asthma is crucial for devising effective prevention and management strategies. At the same time, the therapeutic potential of specific nutrients and bioactive compounds in improving respiratory function, reducing bronchial inflammation, alleviating symptoms, and preventing airway remodeling offers new therapeutic targets for personalized nutrition therapy which could modify the course of asthma, optimize asthma control, and ultimately improve the quality of life for patients and families.

This Special issue endeavors to explore the latest advances in nutritional research and clinical insights related to asthma in pediatric populations. Health professionals including researchers, physicians, and public health experts are invited to contribute their expertise, offering a comprehensive summary of the current state of knowledge, addressing critical questions, and filling gaps in our understanding surrounding pediatric asthma’s epidemiology, pathobiology, and potential avenues for future research and therapeutic intervention. Through collaboration and knowledge exchange, we hope to advance our understanding of pediatric respiratory health, setting the foundations for the development of innovative and evidence-based strategies to improve health outcomes for future generations. While diet alone is not a cure for pediatric asthma, it can play an important part in managing the condition.

Dr. Maria Michelle Papamichael
Dr. Charis V. Katsardis
Guest Editors

Manuscript Submission Information

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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • childhood asthma
  • pulmonary function
  • bronchial inflammation
  • exhaled nitric oxide
  • nutrition
  • dietary patterns
  • Mediterranean diet
  • vitamin D
  • folic acid
  • omega-3 fatty acids
  • lipids
  • asthma pathophysiology and mechanisms
  • asthma metabolomics and lipidomics
  • maternal nutrition

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Published Papers (1 paper)

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Research

15 pages, 1330 KiB  
Article
Erythrocyte Fatty Acid Profile, Mediterranean Diet and Asthma Severity in Childhood Allergic Asthma: Preliminary Findings from a Cohort Study in Spain
by Roser Ayats-Vidal, Isabela-Adelina Albiciuc, Carlota Bruch-Molist, Anna Cuartero-Gorjón, Begoña Cordobilla, Marina Pedrosa-Domínguez, Marta Susanna-Calero, Miguel García-González, Laura Valdesoiro-Navarrete, Helena Larramona-Carrera, Oscar Asensio-de la Cruz, Jesus Castro-Marrero and Joan Carles Domingo
Nutrients 2025, 17(7), 1161; https://doi.org/10.3390/nu17071161 - 27 Mar 2025
Viewed by 426
Abstract
Background: Allergic asthma incidence is increasing, probably due to the influence of the Western diet. Adherence to the Mediterranean diet (MedDi) and omega-3 fatty acids composition (n-3 PUFAs) may be linked to a lower prevalence and lower severity of childhood [...] Read more.
Background: Allergic asthma incidence is increasing, probably due to the influence of the Western diet. Adherence to the Mediterranean diet (MedDi) and omega-3 fatty acids composition (n-3 PUFAs) may be linked to a lower prevalence and lower severity of childhood asthma; however, the association is inconclusive. This study aims to examine the relationship between adherence to the MedDi, asthma severity, and erythrocyte fatty acid profile in Spanish children with atopic asthma. Methods: This study was based on an ongoing single-center, prospective, cross-sectional cohort study involving 95 consecutively enrolled children from an outpatient tertiary referral center. Of these, 55 had atopic asthma and 40 were age-matched healthy controls. Blood samples were collected to analyze the erythrocyte fatty acid content. Participants’ demographic and clinical characteristics were recorded using validated self-reported outcome measures. Asthma severity and pulmonary function were assessed. Results: Asthmatics presented poorer adherence to the MedDi (p = 0.034) and lower n-3 PUFA levels (p = 0.019). Asthmatics with poor adherence to the MedDi were more likely to be overweight (p = 0.001) and to have moderate-severe asthma (p = 0.049); and lower n-3 PUFAs levels (p = 0.033). Children with mild asthma had higher n-3 PUFAs levels than those with moderate or severe asthma (p = 0.036). Conclusions: These findings highlight that adherence to the MedDi and a high erythrocyte fatty acid profile seem to have a protective effect in childhood asthma. Future well-controlled interventions should focus on the effects of MedDi patterns and n-3 PUFA intake on the primary prevention of childhood asthma. Full article
(This article belongs to the Special Issue Diet and Nutrition for Pediatric Asthma)
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