nutrients-logo

Journal Browser

Journal Browser

Dietary Interventions for the Prevention and Treatment of Osteoporosis

A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Clinical Nutrition".

Deadline for manuscript submissions: closed (15 September 2025) | Viewed by 2209

Special Issue Editors


E-Mail Website
Guest Editor
MD Anderson Cancer Center, The University of Texas, Houston, TX 77030, USA
Interests: bone cancer; breast cancer; exercise; musculoskeletal disorders; biomechanics; physical activity; diet
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
Department of Medicine, Division of Endocrinology and Metabolism, UNC School of Medicine, Chapel Hill, NC, USA
Interests: metabolic bone disease; osteoporosis; lipodystrophies; general endocrinology

Special Issue Information

Dear Colleagues,

Skeletal health is orchestrated through a delicate balance of bone formation and resorption, maintaining the biological and structural integrity of the skeleton. Heightened disruption of this balance leads to skeletal disorders such as osteoporosis, a condition which presents a significant healthcare burden, particularly in susceptible populations.

Extensive research has focused on understanding the critical role of diet on musculoskeletal tissue health, and the influence of nutrient supplementation as impactful to the viability and functionality of bone-remodeling cells has garnered increased interest for its potential support for and improvement of bone metabolism and health. Identifying how human diet could be optimized to preserve musculoskeletal health and suppress the onset of skeletal decline and osteoporosis remains of central importance in the field.

Our Special Issue, “Dietary Interventions for the Prevention and Treatment of Osteoporosis”, solicits submissions for original research, reviews, and meta-analyses examining the effects of dietary contributions as preventative or therapeutic interventions for the improvement of bone formation by reestablishing balanced bone turnover and suppressing bone loss. Elucidating the cellular and molecular mechanisms governing these effects may offer valuable guidance for the prevention and treatment of metabolic bone diseases.

We look forward to your contribution to this engaging and critical area of research.

Dr. Gabriel M. Pagnotti
Dr. Maya Styner
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Nutrients is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • bone
  • metabolism
  • bioenergetics
  • skeletal muscle
  • diet
  • osteoporosis
  • osteopenia
  • nutrition
  • bone cancer
  • bone remodeling
  • musculoskeletal health
  • supplementation
  • mineral deficiency

Benefits of Publishing in a Special Issue

  • Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
  • Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
  • Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
  • External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
  • Reprint: MDPI Books provides the opportunity to republish successful Special Issues in book format, both online and in print.

Further information on MDPI's Special Issue policies can be found here.

Published Papers (1 paper)

Order results
Result details
Select all
Export citation of selected articles as:

Other

22 pages, 1885 KB  
Systematic Review
Comparing the Effects of Dairy and Soybean on Bone Health in Women: A Food- and Component-Level Network Meta-Analysis
by Li You, Langrun Wang, Shiwen Zhou, Yiran Guan, Yan Liu, Ruixin Zhu, Huiyu Chen, Jie Guo, Keji Li, Xingyu Bao, Haotian Feng, Ignatius M. Y. Szeto, Jian He, Ran Wang and Jingjing He
Nutrients 2025, 17(17), 2833; https://doi.org/10.3390/nu17172833 - 30 Aug 2025
Viewed by 1809
Abstract
Background/Objectives: Dairy and soybean are important potential dietary sources of bone health. However, their comparative effectiveness and the role of specific components remain unclear. In this network meta-analysis (NMA), we aimed to compare the effects of various dairy and soy products (food [...] Read more.
Background/Objectives: Dairy and soybean are important potential dietary sources of bone health. However, their comparative effectiveness and the role of specific components remain unclear. In this network meta-analysis (NMA), we aimed to compare the effects of various dairy and soy products (food level) and their key bioactive components (component level) on bone health in healthy women. Methods: We systematically searched PubMed, Embase, Cochrane Library, and Web of Science (up to 28 February 2025) for randomized controlled trials. A frequentist random-effects NMA was used to compare interventions for lumbar spine (LS) and total body (TB) bone mineral density (BMD) and bone turnover markers [osteocalcin (OC), deoxypyridinoline (DPD)]. Mean differences (MDs) and 95% confidence intervals were pooled. Interventions were ranked using the surface under the cumulative ranking curve (SUCRA). Results: Sixty RCTs involving 6284 participants (mean age: 54.2 years) were included. At the food level, no dairy or soy interventions significantly improved outcomes versus control, although milk + yogurt ranked numerically highest based on SUCRA values. At the bioactive-component level, the combination of casein + whey protein (MD 0.04 g/cm2, 95% CI 0.01–0.06) and soybean protein (MD: 0.03 g/cm2, 95% CI: 0.01–0.05) significantly increased TB BMD. Whey protein alone (SUCRA 74.4% for LS BMD) and casein + whey protein (SUCRA 86.3% for TB BMD and 75.9% for DPD) were among the highest-ranked interventions for bone health. Conclusions: The combination of milk and yogurt may be relatively promising among dairy products for bone health. Whey protein appears to be a key bioactive component beneficial for women’s bone health. Full article
Show Figures

Figure 1

Back to TopTop