nutrients-logo

Journal Browser

Journal Browser

Nutrition and Diet in Prevention and Treatment of Liver Cancer

A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Nutritional Epidemiology".

Deadline for manuscript submissions: closed (25 July 2025) | Viewed by 213

Special Issue Editor


E-Mail Website
Guest Editor
Department of Epidemiology, School of Public Health, Fudan University, Shanghai 200032, China
Interests: chronic diseases; epidemiology; cancer; liver cancer; non-alcoholic fatty liver disease; nutrition

Special Issue Information

Dear Colleagues,

Liver cancer is a significant global health burden and the third-leading cause of cancer-related deaths worldwide. Diet and nutrition are emerging as key modifiable factors that may influence liver cancer risk and prognosis. Research suggests that a high intake of red meat and dietary sugar are positively correlated with hepatocellular carcinoma (HCC) occurrence, while a high consumption of white meat, fish, vegetables, fruits, cereals, and whole grains is inversely associated with HCC risk. However, the relationship between diet and liver cancer is complex, and further investigation is required in order to clarify these associations and better understand the role of dietary factors in liver cancer development and progression. We are pleased to invite you to submit original research or systematic reviews exploring these relationships, with the aim of developing effective dietary interventions for the prevention and treatment of liver cancer.

We look forward to receiving your contributions.

Dr. Xing Liu
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Nutrients is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • liver cancer
  • hepatocellular carcinoma
  • diet
  • nutrition
  • epidemiology

Benefits of Publishing in a Special Issue

  • Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
  • Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
  • Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
  • External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
  • Reprint: MDPI Books provides the opportunity to republish successful Special Issues in book format, both online and in print.

Further information on MDPI's Special Issue policies can be found here.

Published Papers (1 paper)

Order results
Result details
Select all
Export citation of selected articles as:

Research

13 pages, 1087 KiB  
Article
Tea Consumption and Liver Cancer: A Population-Based Case–Control Study in Eastern China
by Xing Liu, Aileen Baecker, Ming Wu, Jinyi Zhou, Ziyi Jin, Lina Mu, Na He, Jianyu Rao, Qing-Yi Lu, Liming Li, Jin-Kou Zhao and Zuo-Feng Zhang
Nutrients 2025, 17(16), 2647; https://doi.org/10.3390/nu17162647 - 15 Aug 2025
Abstract
Background/Objectives: Identifying dietary factors influencing liver cancer is crucial for developing preventive measures. While tea polyphenols have demonstrated cancer-preventive activities in animal models, the evidence in humans is not definitive. This study aims to explore the association between tea consumption and liver [...] Read more.
Background/Objectives: Identifying dietary factors influencing liver cancer is crucial for developing preventive measures. While tea polyphenols have demonstrated cancer-preventive activities in animal models, the evidence in humans is not definitive. This study aims to explore the association between tea consumption and liver cancer, as well as the interaction between tea drinking and other risk factors, in China, a country with a high incidence of liver cancer and substantial tea consumption. Methods: A population-based case–control study was conducted in Jiangsu Province from 2003 to 2010. Socio-demographic data, history of tea consumption, and serum markers of hepatitis B virus (HBV) and hepatitis C virus (HCV) infections were evaluated. Unconditional logistic regression was used to examine the associations between tea consumption and the odds of liver cancer. Potential interactions between tea consumption and other major liver cancer risk factors were assessed. Results: A total of 2011 incident liver cancer cases and 7933 controls were included in the analysis. Regular tea drinking showed an inverse association with the risk of liver cancer compared with those who never drank tea (OR: 0.79; 95% CI: 0.63–0.99). Current tea drinking showed an inverse association with liver cancer (OR: 0.51; 95% CI: 0.39–0.66), while former tea drinking showed a positive association (OR: 3.56; 95% CI: 2.42–5.23). Current tea consumption was inversely associated with liver cancer incidence among both hepatitis B surface antigen (HBsAg) positive (OR: 0.45; 95% CI: 0.28–0.73) and HBsAg negative participants (OR: 0.51, 95% CI: 0.36–0.73), among both never and ever tobacco smokers, ever alcohol drinkers (OR: 0.46; 95% CI: 0.33–0.63), and among those without family history of liver cancer. Multiplicative and additive interactions were observed between tea drinking and HBsAg, alcohol consumption, and history of raw water drinking. Conclusions: Tea consumption is inversely associated with the development of primary liver cancer, with potential interactions involving HBV infection, alcohol consumption, and raw (unsafe) water drinking. Increasing tea consumption—particularly among high-risk populations such as individuals who consume alcohol—may serve as an additional preventive measure for liver cancer. This should be considered alongside established strategies, including HBV vaccination, alcohol cessation, and avoidance of drinking raw water, to help reduce liver cancer risk. Full article
(This article belongs to the Special Issue Nutrition and Diet in Prevention and Treatment of Liver Cancer)
Show Figures

Figure 1

Back to TopTop