nutrients-logo

Journal Browser

Journal Browser

Polyphenols in Foods and Their Impact on Human Health and Diseases

A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Phytochemicals and Human Health".

Deadline for manuscript submissions: 25 October 2025 | Viewed by 1289

Special Issue Editor


E-Mail Website
Guest Editor
Department of Nutrition, Graduate School of Human Life and Ecology, Osaka Metropolitan University, Osaka 558-8585, Japan
Interests: lifestyle-related diseases; functional food components; reactive oxygen species; bioactive nutrients; antioxidant activity
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Polyphenols, abundant in a wide variety of plant-based foods such as vegetables, fruits, and beverages, have attracted significant attention due to their potential antioxidant and anti-inflammatory properties. As well as these well-known benefits, they influence a broad spectrum of physiological processes, playing a critical role in combating lifestyle-related diseases.

However, many aspects of polyphenols and their physiological effects remain unexplored, presenting an exciting opportunity to uncover new insights into their potential for improving health and preventing disease.

For this Special Issue, we invite researchers from diverse disciplines to contribute original studies and reviews that explore the intricate mechanisms and effects of polyphenols. We welcome investigations employing in vitro, in vivo, and human clinical models that delve into the connections between polyphenol-rich diets and human health.

We invite you to join us in advancing this vital area of research and sharing findings that could pave the way for innovative approaches to health and wellness.

Dr. Akiko Kojima-Yuasa
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Nutrients is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • antioxidants
  • reactive oxygen species
  • Nrf2
  • lifestyle-related diseases
  • obesity
  • cancer
  • neurodegenerative diseases
  • inflammatory diseases
  • cardiovascular diseases

Benefits of Publishing in a Special Issue

  • Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
  • Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
  • Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
  • External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
  • e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.

Further information on MDPI's Special Issue policies can be found here.

Published Papers (1 paper)

Order results
Result details
Select all
Export citation of selected articles as:

Other

9 pages, 2126 KiB  
Brief Report
Taxifolin as a Therapeutic Potential for Weight Loss: A Retrospective Longitudinal Study
by Yorito Hattori, Yuriko Nakaoku, Soshiro Ogata, Satoshi Saito, Kunihiro Nishimura and Masafumi Ihara
Nutrients 2025, 17(4), 706; https://doi.org/10.3390/nu17040706 - 16 Feb 2025
Viewed by 1093
Abstract
Background/Objectives: The current approach to obesity care, which primarily focuses on weight loss, is often insufficient because of the challenges in maintaining long-term results. Therefore, novel, safe, and sustainable medications for obesity are highly anticipated. Taxifolin, a natural bioactive flavonoid, was found to [...] Read more.
Background/Objectives: The current approach to obesity care, which primarily focuses on weight loss, is often insufficient because of the challenges in maintaining long-term results. Therefore, novel, safe, and sustainable medications for obesity are highly anticipated. Taxifolin, a natural bioactive flavonoid, was found to exert pleiotropic protective effects against various diseases. Our experimental in vivo and in vitro studies revealed that taxifolin administration contributes to weight loss. Accordingly, we hypothesized that long-term oral intake of taxifolin was clinically associated with weight loss. Methods: A retrospective longitudinal study was conducted on participants who consistently monitored their body weight during routine clinic visits between January 2021 and July 2021. Body weight changes of the patients who received 300 mg/day of taxifolin were compared with those of patients who did not receive taxifolin. Results: The study enrolled a total of 62 patients: 36 received taxifolin and 26 did not receive taxifolin. Long-term intake of taxifolin showed greater weight loss than those not receiving taxifolin over a mean follow-up of 176.1 and 177.7 days, respectively (−1.6 vs. −0.3 kg; p = 0.026). Furthermore, long-term taxifolin intake was an independent predictor of increased weight loss (adjusted β [mean difference] −0.14, 95% confidence interval [−2.69, −0.18], p = 0.026). No adverse events were observed. Conclusions: Long-term daily oral intake of taxifolin may safely and sustainably prevent or manage obesity. Full article
(This article belongs to the Special Issue Polyphenols in Foods and Their Impact on Human Health and Diseases)
Show Figures

Figure 1

Back to TopTop