Dietary Factors Associated with Microbiota in Gastrointestinal Cancer
A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Nutritional Immunology".
Deadline for manuscript submissions: 5 September 2026 | Viewed by 308
Special Issue Editor
2. Diet, Microbiota, and Health Group, Instituto de Investigación Sanitaria del Principado de Asturias (DIMISA, Health Research Institute of Asturias), 33004 Oviedo, Spain
Interests: microbiome; probiotics; prebiotics; xenobiotics; polyphenols; fibers; colorectal cancer
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Gastrointestinal (GI) cancers—including colorectal, gastric, pancreatic, oesophageal, and hepatobiliary malignancies—remain a major global health challenge. Increasing evidence shows that the interplay between dietary exposures, gut microbiota composition and function, and host inflammatory responses plays a central role in the initiation, progression, and clinical behaviour of GI cancers. As research continues to uncover how diet‑driven microbial metabolites, dysbiosis, and microbe–host interactions influence carcinogenic pathways, the microbiota has emerged as a key modifiable factor with substantial implications for prevention and therapy.
This Special Issue aims to gather cutting‑edge research and comprehensive reviews exploring how dietary patterns, specific nutrients, food processing levels, and bioactive compounds shape the gut microbiota and, in turn, modulate gastrointestinal tumorigenesis. We particularly welcome studies addressing mechanisms through which microbiota‑mediated metabolic and immunological pathways contribute to cancer risk and progression, as well as investigations linking dietary interventions, microbial signatures, and clinical outcomes.
Contributions examining microbiota‑related biomarkers, diet–microbiome–inflammation interactions, microbial metabolites, and microbiota‑targeted strategies for prevention or treatment are strongly encouraged. By fostering interdisciplinary dialogue between nutrition science, microbiome research, oncology, and public health, this Special Issue seeks to advance our understanding of diet–microbiota interactions in GI cancer and support the development of innovative, evidence‑based approaches for risk reduction and patient management.
Dr. Sonia González
Guest Editor
Manuscript Submission Information
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Keywords
- microbiome
- gastrointestinal cancer
- polyphenol
- fibers
- inflammation
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