New Insights into the Immunomodulatory Effects of Exercise, Nutrition and Supplementation on Aging, Health, Disease and Performance – What Have We Learned from Pre-clinical and Clinical Studies?

Dear Colleagues,

There is a growing body of scientific evidence demonstrating the beneficial effects of non-pharmacologic interventions, such as physical activity, nutrition, and dietary supplements, in preventing and helping in the treatment of diseases, as well as promoting healthy aging. Beyond that, adequate nutritional support, including dietary supplements, is proven to be beneficial for recreative and professional athletes, leading to better performance, preventing injury, and improving recovery. In this context, several pre-clinical studies (in vitro, ex vivo, and in animal models) have been performed, aiming, for the most part, to demonstrate the cellular and molecular mechanisms involved. In addition, many studies have demonstrated not only the clinical outcomes obtained in different populations resulting from physical activity and nutrition interventions but also the immunological mechanisms involved in such effects. On the other hand, excessive physical activity, dietary supplements, or the wrong dietary strategy may result in injuries, favor the establishment of diseases, or even cause exacerbations of diseases. So, in this wonderful, great, and complex world of exercise, nutrition, and immunology, we invite our colleagues to submit their mini-review, review, systematic review, and original (pre-clinical and clinical studies) to our Special Issue in the journal Nutrients, which has been entitled “New Insights into the Immunomodulatory Effects of Exercise, Nutrition, and Supplementation on Aging, Health, Disease, and Performance – What Have We Learned from Pre-clinical and Clinical Studies?”. 

Prof. Dr. Rodolfo de Paula Vieira
Dr. André L.L. Bachi
Guest Editors

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• immunonutrition
• exercise immunology
• immunoaging
• immunosuppression
• nutrition
• dietary supplements
• sports performance