Special Issue "Protein Nanomechanics"
A special issue of Nanomaterials (ISSN 2079-4991).
Deadline for manuscript submissions: 25 October 2020.
Interests: protein folding; structure and function; single-molecule experiments; mechanical forces; chaperones; protein stability
Proteins are fascinating, complex biomacromolecules that are involved in nearly every process in the cell. For the effective performance of their in vivo function, the nanomechanical properties of proteins need to be balanced between conflicting demands: on the one hand, the mechanical integrity of a protein is often a prerequisite for a function, e.g., protein–biomolecule interactions, the maintenance of cell morphology, and enzyme catalysis; on the other hand, a very high mechanical stability interferes with the conformational dynamics of proteins, and high protein rigidity can affect downstream processes such as degradation and turnover control.
Apart from their importance for the cell, the applied research scientists have started to examine how to design synthetic biomaterials with tailor-made mechanical properties, which can function as, for example, biological tissue surrogates.
The purpose of the Special Issue is to gain new fundamental knowledge on proteins to reveal their balanced nanomechanics and potential applications in material science.
Dr. Gabriel Žoldák
Manuscript Submission Information
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- mechanical force
- biological nanomaterials