Special Issue "Nanoparticles in Neurology"
A special issue of Nanomaterials (ISSN 2079-4991).
Deadline for manuscript submissions: closed (30 November 2017).
Interests: lipid/protein nanoassemblies; liquid crystalline phases; cubosomes; self-assembled nanostructures and nanoparticles with neuroprotective properties; protein and peptide-based nanomedicines; nanocarriers for macromolecular drug delivery; membrane receptor nanoscale organization; lipids; peptides; BDNF; cyclodextrin; soft nanomaterials
Special Issues and Collections in MDPI journals
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Special Issue in Nanomaterials: Self-Assembly, Synthetic and Biomimetic Nanostructures
Development of therapeutic systems for targeting the central nervous system (CNS) in neurological disorders is quite challenging and requires new concepts to achieve neuronal and synaptic repair, as well as neurogenesis in adult brain. Recent evidence suggests that macromolecular drugs (antibodies and other therapeutic proteins, peptides, and nucleic acids) provide higher efficiency and specificity as compared to small molecular weight compounds. However, these molecules have very low bioavailability and marginal capacity to cross the blood-brain barrier (BBB).
This Special Issue focuses on emergent neuronanomedicines derived from functionalized nanoparticles that may cross the BBB and deliver therapeutic molecules to target sites in the CNS. Topical delivery by nanocarriers exerting disease-modifying action on neurodegenerative and other neurological disorders will be of special interest. All kinds of nanocarrier formulations that may show neuroprotective activity, recovery from oxidative stress and ischemic injury as well as slow down and prevent neurodegeneration, will be considered in view of potential translational research in pathologies such as Alzheimer’s disease, Parkinson’s disease, Hungtington’s disease, stroke, amyotrophic lateral sclerosis, Rett syndrome, hearing impairment, spinal cord injury, multiple sclerosis, etc.
Dr. Angelina Angelova
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
targeted delivery to the CNS
nanocarriers of peptide and proteins drugs
nanocarriers of nucleic acids
nanoparticles with disease-modifying action on neurodegenerative disorders
nanoparticles for synaptic repair
neuropharmacology of nanomaterials
neurogenesis, neuroprotection, neuroplasticity, neurotoxicity
nanoparticles for recovery from oxidative stress and ischemic injury
nanoparticles and intracellular signaling pathways
neuronanomedicines derived from lipid, polymer, mesoporous or hybrid nanomaterials