Special Issue "Graphene Based Nanocomposites for Antibacterial Applications and Biosensors"

A special issue of Nanomaterials (ISSN 2079-4991).

Deadline for manuscript submissions: closed (20 April 2019).

Special Issue Editors

Prof. Dr. Ivan Mijakovic
Website
Guest Editor
Department of Biology and Biological Engineering, Chalmers University of Technology, SE-412 96 Göteborg, Sweden
Interests: graphene-based antibacterial coatings; graphene-based bio-sensors; protein phosphorylation; bacterial cells; metabolic engineering; industrially relevant enzymes and nanoparticles
Prof. Dr. August Yurgens
Website
Guest Editor
Department of Microtechnology and Nanoscience, Chalmers University of Technology, SE-412 96 Göteborg, Sweden
Interests: graphite and garphene; semimetals; bismuth; transport and magnetic properties of HTSC, physics of vortices; physics and application of the intrinsic Josephson effect

Special Issue Information

Dear Colleagues,

The interaction of graphene with living cells opens up several interesting fields of application. Due to their hydrophobic nature, thin layers of graphene can penetrate biological membranes. Graphene flakes or sheets are also known to wrap around cells. These processes can lead to cellular damage, both via disruption of the membrane lipid bilayer or induction of oxidative stress. Bacteria are especially susceptible to damage caused by graphene and this has recently led to interesting advances in antibacterial applications of graphene-based nanocomposites. Another aspect of graphene useful in bio-applications is its extreme sensitivity to electrical perturbations. Charged moieties approaching the graphene sheet affect its electrical conductivity, and this can be readily measured. Based on this property, there are efforts to develop various graphene-based nano-devices that can operate as sensors. These range from sensors of small molecules/metabolites, peptides and proteins, to detection of whole bacterial cells attaching to surfaces.

Prof. Dr. Ivan Mijakovic
Prof. Dr. August Yurgens
Guest Editors

Manuscript Submission Information

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Keywords

  • grapheme
  • infection
  • biofilm
  • implant
  • antibacterial coating
  • biosensor

Published Papers (1 paper)

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Review

Open AccessReview
Antibacterial Properties of Graphene-Based Nanomaterials
Nanomaterials 2019, 9(5), 737; https://doi.org/10.3390/nano9050737 - 13 May 2019
Cited by 15
Abstract
Bacteria mediated infections may cause various acute or chronic illnesses and antibiotic resistance in pathogenic bacteria has become a serious health problem around the world due to their excessive use or misuse. Replacement of existing antibacterial agents with a novel and efficient alternative [...] Read more.
Bacteria mediated infections may cause various acute or chronic illnesses and antibiotic resistance in pathogenic bacteria has become a serious health problem around the world due to their excessive use or misuse. Replacement of existing antibacterial agents with a novel and efficient alternative is the immediate demand to alleviate this problem. Graphene-based materials have been exquisitely studied because of their remarkable bactericidal activity on a wide range of bacteria. Graphene-based materials provide advantages of easy preparation, renewable, unique catalytic properties, and exceptional physical properties such as a large specific surface area and mechanical strength. However, several queries related to the mechanism of action, significance of size and composition toward bacterial activity, toxicity criteria, and other issues are needed to be addressed. This review summarizes the recent efforts that have been made so far toward the development of graphene-based antibacterial materials to face current challenges to combat against the bacterial targets. This review describes the inherent antibacterial activity of graphene-family and recent advances that have been made on graphene-based antibacterial materials covering the functionalization with silver nanoparticles, other metal ions/oxides nanoparticles, polymers, antibiotics, and enzymes along with their multicomponent functionalization. Furthermore, the review describes the biosafety of the graphene-based antibacterial materials. It is hoped that this review will provide valuable current insight and excite new ideas for the further development of safe and efficient graphene-based antibacterial materials. Full article
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