Special Issue "Nanomechanics: From Theory to Application"

A special issue of Nanomaterials (ISSN 2079-4991).

Deadline for manuscript submissions: 31 May 2021.

Special Issue Editors

Dr. Marina Inés Giannotti
Guest Editor
Biomedical Research Networking Center on Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), Institute for Bioengineering of Catalonia (IBEC), The Barcelona Institute of Science and Technology, Baldiri Reixac 15-21, 08028 Barcelona, Spain
Department of Materials and Physical Chemistry, Faculty of Chemistry, Universitat de Barcelona (UB), Barcelona, Spain
Interests: nanomechanics; biophysics; lipid membranes; single molecules; force spectroscopy; atomic force microscopy
Dr. Lorena Redondo-Morata
Guest Editor
Center for Infection and Immunity of Lille, INSERM U1019, CNRS UMR 8204, F-59000 Lille, France
Interests: biophysics; membrane remodeling; lipid membranes; nanomechanics; membrane dynamics; atomic force microscopy; high-speed force spectroscopy; force spectroscopy

Special Issue Information

Dear Colleagues,

Nanomechanics is an area of nanoscience that studies fundamental mechanical properties of physical systems at the nanoscale. Nanomechanics has developed at the intersection of classical mechanics, statistical mechanics, and quantum chemistry, and the overlapping of solid-state physics, biophysics, and materials science.

In nature, all key steps involve mechanical movement at the molecular level, and, moreover, the macroscopic properties of polymeric materials are closely related to the molecular composition, structure, conformation, and interactions at this level.

Nanomechanical studies of single macromolecules contribute to the comprehension of fundamental aspects concerning their structural, mechanical, and binding properties. Understanding the elastic behavior, or deformation, of individual macromolecules is an essential issue in both biophysics and materials science. Viscoelastic relaxation provides polymers and thin films with time-dependent properties necessary for energy dissipation and frequency-dependent stiffening or reswelling, among others. The forces that hold molecules together in supramolecular structures are generally weak intermolecular forces or interactions. Such interactions play a relevant role in the physical properties and function of nanostructures and biological entities.

The development of experimental nanoscale and single-molecule manipulation methods has allowed for the tracking of individual species and the precise application and measurement of minute forces, opening new perspectives in life sciences as well as in materials science. This has particular importance in areas where temporal and spatial averaging is to be avoided, mechanical forces need to be measured, and individual species are to be tracked. Among them, the most common are the mechanical transducers, such as microneedles and atomic force microscopy-based force spectroscopy (AFM-FS), and the external field manipulators, such as hydrodynamic flow and magnetic or optical traps (magnetic or optical tweezers), which have permitted studies on the role of the mechanosensitive proteins and lipids in membranes, protein folding or DNA mechanics, the elasticity of macromolecules, the mechanical work generated by molecular motors, and cell and tissue mechanics.

This Special Issue of Nanomaterials, entitled “Nanomechanics: From Theory to Application”, will cover the aforementioned advances, comprising both theoretical and experimental findings in different areas from nanostructures and materials to biological entities.

Dr. Marina Inés Giannotti
Dr. Lorena Redondo-Morata
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Nanomaterials is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • nanomechanics
  • single molecules
  • forces
  • polymers
  • macromolecules
  • thin films
  • biophysics
  • force spectroscopy
  • AFM
  • optical tweezers.

Published Papers

This special issue is now open for submission.
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