Nanoscale Metal–Organic Frameworks for Cancer Therapy
A special issue of Nanomaterials (ISSN 2079-4991). This special issue belongs to the section "Inorganic Materials and Metal-Organic Frameworks".
Deadline for manuscript submissions: 20 January 2026 | Viewed by 5
Special Issue Editor
Interests: synthesis of MOFs and MOF composites; drug delivery; fire safety of polymers; CO2 adsorption
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
In recent years, nanoscale metal–organic frameworks (NMOFs) have emerged amongst the most promising platforms in the field of cancer nanomedicine. Constructed from metal ions or clusters coordinated in relation to organic ligands, NMOFs offer unique advantages such as tunable porosity, high surface area, multifunctional capabilities, and ease of functionalization. These properties allow for the precise delivery of therapeutic agents, controlled drug release, imaging-guided therapy, and synergistic treatment approaches—including chemotherapy, photodynamic therapy (PDT), photothermal therapy (PTT), immunotherapy, and chemodynamic therapy (CDT). This Special Issue aims to highlight the latest developments and cutting-edge research in the design, synthesis, and biomedical applications of NMOFs for cancer therapy. It will cover novel strategies for enhancing biocompatibility, tumor-targeting efficiency, and stimuli-responsiveness, and overcoming physiological barriers in the tumor microenvironment. Additionally, contributions focusing on clinical translation challenges, toxicity evaluation, and multifunctional theranostic systems are encouraged. By gathering insights from materials science, chemistry, bioengineering, and oncology, this Issue seeks to foster interdisciplinary collaboration and stimulate innovative approaches for the next generation of nanotherapeutics. We invite the submission of original research articles, reviews, and perspectives that explore the therapeutic potential and translational prospects of NMOFs in combating cancer.
Dr. Hafezeh Nabipour
Guest Editor
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Keywords
- nanoscale metal–organic frameworks (NMOFs)
- cancer nanomedicine
- drug delivery
- photodynamic therapy (PDT)
- photothermal therapy (PTT)
- chemodynamic therapy (CDT)
- tumor targeting
- stimuli-responsive systems
- theranostics
- clinical translation
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