Toxicity of Engineered Nanomaterials: Current Understanding and Challenges

Dear Colleagues,

The use of engineered nanomaterials (ENMs) in consumer and biomedical products is growing rapidly, leading to an increase in organismal exposure to these materials. As a result, it is crucial to understand their safety implications, which is of paramount importance to the public. In certain critical sectors such as construction materials, metallurgy, mining, and conservation and restoration, there is a significant risk associated with the emission of nanomaterials. Despite the use of various animal models and cell-line-based simulations to evaluate the toxicity and underlying mechanisms of nanomaterials, our understanding of nanotoxicity mechanisms remains limited. Therefore, there is a need to develop a more comprehensive understanding of this issue and identify potential solutions.

This Special Issue aims to consolidate our current knowledge and the challenges related to the toxicity of ENMs. By doing so, it has significant predictive potential in expanding our understanding of the potential biological effects, behavior, and underlying mechanisms of ENMs in mammals and humans.

This Special issue will welcome manuscripts on the following topics:

• Safety evaluation and toxicological mechanisms of emerging nanomaterials;
• Chemical modification-based screening of low-toxicity nanomaterials;
• Adverse outcome pathways (AOPs) and predictive nanotoxicology;
• Pharmacological strategies and toxicity prevention of nanomaterials;
• Removal technology and mechanism of nanomaterials;
• Ecotoxicological evaluation and toxicology models in model animals.

Dr. Man Qu
Dr. Luz Stella Gomez-Villalba
Guest Editors

Manuscript Submission Information

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