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Diamondoids and Their Derivatives

A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Organic Chemistry".

Deadline for manuscript submissions: closed (15 October 2016) | Viewed by 15051

Special Issue Editors


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Guest Editor
National Technical University of Ukraine, Kiev Polytechnic Institute, Kiev, Ukraine
Interests: chemistry of cage compounds (dimondoids and cubanes); C–H activation mechanisms; hydrocarbon radical cations; chemistry of ylides; computational chemistry

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Guest Editor
Geballe Laboratory for Advanced Materials, Stanford University, Stanford, CA 94305, USA

Special Issue Information

Dear Colleagues,

Three-dimensional polycyclic rigid structures (also called “cage compounds”) are of great importance both for practical and theoretical chemistries. Many basic chemical concepts were developed with the cage compounds as models (steric effect, hyperconjugation, electron transfer). There are also many beautiful and aesthetically attractive molecules of this class, from Platonic Bodies, such as tetrahedrane, cubane, and dodecahedrane to naturally occurring diamondoids, of which the most well-know representative is adamantane. There has been enormous recent development of the chemistry of cage compounds, mainly targeting material and medicinal applications. Among the successful attempts are the replacement the 2D-aromatic fragments of drugs by topologically related hydrophobic cages, the applications of diamondoid derivatives in nanoelectronics, the preparation of new polymeric materials. The ability of diamondoid derivatives to mimic the key electronic properties of natural diamond opens new avenues in the development of diamond-like organic electronics joining the efforts of chemists, physicists, and material scientists. Additionally, the rigidity of the cages allows the use of their derivatives as building blocks for assembling of various supramolecular structures.

The aim of this Special Issue is to reflect the current fundamental and practical aspects of diamondoid chemistry including both rigid organic and mixed organic/inorganic structures.

The online-publishing Special Issue of Molecules will welcome all kind of submissions that fit the above outline.

Prof. Dr. Andrey A. Fokin
Dr. Nicholas A. Melosh
Guest Editors

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Keywords

  • diamondoids
  • functional derivatives
  • adamantane
  • diamantane
  • diamond building blocks
  • applications
  • electronic properties
  • diamond-like materials

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Published Papers (1 paper)

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Review

14 pages, 3962 KiB  
Review
Adamantane in Drug Delivery Systems and Surface Recognition
by Adela Štimac, Marina Šekutor, Kata Mlinarić-Majerski, Leo Frkanec and Ruža Frkanec
Molecules 2017, 22(2), 297; https://doi.org/10.3390/molecules22020297 - 16 Feb 2017
Cited by 136 | Viewed by 14495
Abstract
The adamantane moiety is widely applied in design and synthesis of new drug delivery systems and in surface recognition studies. This review focuses on liposomes, cyclodextrins, and dendrimers based on or incorporating adamantane derivatives. Our recent concept of adamantane as an anchor in [...] Read more.
The adamantane moiety is widely applied in design and synthesis of new drug delivery systems and in surface recognition studies. This review focuses on liposomes, cyclodextrins, and dendrimers based on or incorporating adamantane derivatives. Our recent concept of adamantane as an anchor in the lipid bilayer of liposomes has promising applications in the field of targeted drug delivery and surface recognition. The results reported here encourage the development of novel adamantane-based structures and self-assembled supramolecular systems for basic chemical investigations as well as for biomedical application. Full article
(This article belongs to the Special Issue Diamondoids and Their Derivatives)
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