Next Article in Journal
Physicochemical Characterization and Biological Activities of the Triterpenic Mixture α,β-Amyrenone
Previous Article in Journal
Synthesis and Antitumor Activities of Chiral Dipeptide Thioureas Containing an Alpha-Aminophosphonate Moiety
Article Menu
Issue 2 (February) cover image

Export Article

Open AccessReview

Adamantane in Drug Delivery Systems and Surface Recognition

University of Zagreb, Centre for Research and Knowledge Transfer in Biotechnology, Rockefellerova 10, 10000 Zagreb, Croatia
Department of Organic Chemistry and Biochemistry, Ruđer Bošković Institute, Bijenička cesta 54, 10000 Zagreb, Croatia
Author to whom correspondence should be addressed.
Academic Editor: Andrey A. Fokin
Molecules 2017, 22(2), 297;
Received: 23 December 2016 / Revised: 19 January 2017 / Accepted: 11 February 2017 / Published: 16 February 2017
(This article belongs to the Special Issue Diamondoids and Their Derivatives)
PDF [3962 KB, uploaded 16 February 2017]


The adamantane moiety is widely applied in design and synthesis of new drug delivery systems and in surface recognition studies. This review focuses on liposomes, cyclodextrins, and dendrimers based on or incorporating adamantane derivatives. Our recent concept of adamantane as an anchor in the lipid bilayer of liposomes has promising applications in the field of targeted drug delivery and surface recognition. The results reported here encourage the development of novel adamantane-based structures and self-assembled supramolecular systems for basic chemical investigations as well as for biomedical application. View Full-Text
Keywords: adamantane; targeted drug delivery; liposomes; surface recognition; cyclodextrins; dendrimers adamantane; targeted drug delivery; liposomes; surface recognition; cyclodextrins; dendrimers

Figure 1

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).

Share & Cite This Article

MDPI and ACS Style

Štimac, A.; Šekutor, M.; Mlinarić-Majerski, K.; Frkanec, L.; Frkanec, R. Adamantane in Drug Delivery Systems and Surface Recognition. Molecules 2017, 22, 297.

Show more citation formats Show less citations formats

Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Related Articles

Article Metrics

Article Access Statistics



[Return to top]
Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top