New Insights into Anti-allergic, Anti-asthmatic Materials

Dear Colleagues,

Bioactive natural products (plant, animal, and insect extracts) and their active ingredients can play an important role in anti-inflammatory responses by inhibiting inflammatory mediators and are used as a medicine for the treatment of inflammatory diseases, such as allergic diseases and airway inflammation including asthma, allergic dermatitis, COPD, etc. In allergic diseases and airway inflammation, recruitment of inflammatory cells such as T cells, mast cells, eosinophils, and neutrophils is mediated via a number of chemokines and their receptors. They also play a role in activation and differentiation of inflammatory cells by selectively activating Th1 or Th2 cells or by effects on epithelial or endothelial cells. Chemokines and their receptors are crucial therapeutic targets in allergic diseases and COPD because of their central role in immune cell recruitment and activation during inflammation.

This Special Issue on “New Insights into Anti-Allergic, Anti-Asthmatic Materials” welcomes original research and reviews on: (1) characterization of active ingredients of medicinal plants, animals, insects, etc.; (2) the therapeutic effects and mechanisms of natural products on allergic diseases such as allergic asthma, allergic dermatitis and COPD (chronic obstructive pulmonary disease); (3) the multi-ingredient synergistic effects and therapeutic mechanisms of natural products, their active ingredients, their combinations on allergic diseases, etc.; (4) identification of targets and mechanisms of activity of anti-allergic and anti-asthmatic materials; and (5) critical reviews of the historical, preclinical, and clinical research on natural products, and their active ingredients on allergic diseases and COPD.

Prof. Dr. Young Cheol Lee
Guest Editor

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