Supramolecular Strategies in Medicine and Environmental Science: Biomedical and Remediation Potentials of Cyclodextrins and Hyaluronic Acid
A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Macromolecular Chemistry".
Deadline for manuscript submissions: 15 March 2026 | Viewed by 1
Special Issue Editor
Interests: transport properties; thermodynamic properties; electrolytes; polyelectrolytes; polymers; carbohydrates; drugs
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Cyclodextrins and hyaluronic acid have emerged as pivotal systems in both fundamental and applied research due to their broad spectrum of applications in pharmaceutical chemistry, as well as human and veterinary medicine. Hyaluronic acid (or hyaluronan) is a natural polysaccharide widely used in therapeutic formulations, particularly in dentistry, due to its excellent lubricating, anti-inflammatory, and antibacterial properties. Cyclodextrins, on the other hand, are among the most prominent carriers in drug delivery systems, particularly for local anesthetics and other poorly soluble pharmaceuticals. Their unique structure enables the solubilization and stabilization of hydrophobic drugs, leading to significant improvements in aqueous solubility, diffusion rates, and bioavailability. Despite the growing importance of these supramolecular systems, our understanding of their transport and thermodynamic behavior under physiological conditions remains limited. This knowledge gap poses challenges for the rational design of safer and more effective pharmaceutical formulations. The comprehensive characterization of these systems is, therefore, essential to not only better understand the behavior of different drugs in aqueous environments containing these macrocyclic hosts but also generate valuable data for the scientific and technological communities working on solution transport phenomena and drug formulation modeling.
Dr. Ana Cristina Faria Ribeiro
Guest Editor
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Keywords
- cyclodextrins
- hyaluronic acid
- therapeutic
- drug delivery
- supramolecular
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