Bioactive Natural Products from Microorganisms

Dear Colleagues,

Microbial natural products are characterized by a wide spectrum of biological activities that ensure the adaptation of microorganism to their environment and that mediate their interactions with other organisms. Some of these natural products can be exploited as new drugs or lead compounds in the pharmaceutical, cosmetic, agrochemical, food industries, and others.

There is currently a resurgence of interest in the discovery of structurally novel bioactive compounds from natural sources, largely due to the fact that synthetic libraries have not produced the expected number of candidates for development by the pharmaceutical industry, as well as to the appearance of pathogens resistant to the drugs currently used.

This Special Issue is focused on both original research and review articles that cover the isolation and structural elucidation of new bioactive compounds from microorganism, including new techniques to induce silent biogenetic gene clusters that lead to the discovery of novel cryptic natural products. Evaluation of the biological activities of the novel compounds, their structure–activity relationship, and molecular mechanisms of action are welcomed.

Dr. Rosa M. Durán-Patrón
Guest Editor

Manuscript Submission Information

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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-anonymized peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.