Special Issue "Herbal Medicines as Antivirals"
A special issue of Molecules (ISSN 1420-3049).
Deadline for manuscript submissions: 31 October 2020.
Institute of Molecular and Cell Biology, A*STAR, Singapore
Interests: positive-sense RNA viruses; molecular virology; antiviral strategies (therapeutics and vaccines); natural product antivirals
Interests: emerging and re-emerging viruses; epidemiology surveillance; antiviral mechanism; viral pathogenesis
Emerging and re-emerging infections caused by viruses continue to threaten us. Over the past decades, Ebola virus, SARS and MERS coronavirus, avian influenza viruses, enteroviruses, as well as vector-borne viruses, such as chikungunya, Zika, and dengue, to name but a few, have caused large-scale outbreaks around the world, resulting in huge socioeconomic burden. There is no effective antiviral or vaccine available for clinical applications for many of these emerging and re-emerging viruses. Currently, the management of emerging and re-emerging infections has been limited to supportive treatments, and it is important to develop alternate strategies to identify potential antiviral therapeutics against virus infections.
Herbal medicine traditionally focuses on the use of herbal plants and plant extracts to treat a diverse of human diseases, in fact, a number of modern drugs were originally extracted from plant sources, even if they are now made synthetically. In Ayurveda, about 2000 plant species are considered to have medicinal application, while the Chinese Pharmacopoeia lists over 5700 traditional medicines, mostly of plant origin. Many of the diverse plant species growing throughout the world have medicinal uses, containing active constituents that have direct beneficial effects on the human body. For example, flavanoids have a wide range of actions and many medicinal uses. Some of flavanoids also have anti-inflammatory and antiviral activity, such as quercetin that inhibits the replication of herpes simplex virus type 1 and polio-virus type 1, and baicalein and quercetagetin, which are shown to inhibit chikungunya infection.
In this Special Issue, we are requesting original research articles and reviews focusing on the identification, synthesis, and evaluation of herbal medicine and/or active constituents against viral infections. Studies using antiviral therapeutic approaches and rationales based on herbal medicine are also welcome.
Assoc. Prof. Justin Jang Hann CHU
Dr. Chee Keng MOK
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- active constituents
- plant extracts
- viral infections
- antiviral therapeutics
- virus inhibition