DNA Damage and Repair

Dear Colleagues,

DNA is a molecule of paramount importance due to its fundamental biological role in carrying and storing genetic information. As such, its stability is key for safeguarding DNA integrity from external stress. This is achieved, inter alia, by means of specific repair mechanisms that ensure an efficient and prompt correction of the DNA defects. Nonetheless, some exogenous or endogenous chemical or physical agents may change this well-functioning scenario, provoking the formation of deleterious lesions that, if left unrepaired, threaten cell integrity.

This Special Issue represents an excellent opportunity for researchers of different areas to share their latest progresses and aims at developing a work in the “frontier of knowledge” with an interdisciplinary approach between chemistry (experimental and theoretical), biology, and medicine. The published original articles or reviews will open new paths toward the understanding of the generation and repair of DNA lesions, thus making it possible to advance knowledge of the processes that are at the origin of tumorigenesis.

Dr. Virginie L. Lhiaubet-Vallet
Dr. Daniel Roca-Sanjuán
Prof. Dr. Iñaki Tuñón
Guest Editors

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