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Special Issue "Complex Multifunctional Organic/Inorganic Nanocarriers"

A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Nanochemistry".

Deadline for manuscript submissions: 31 March 2020.

Special Issue Editors

Prof. Luigi Paduano
E-Mail Website1 Website2
Guest Editor
Universita degli Studi di Napoli Federico II, Department of Chemical Sciences, Naples, Italy
Interests: amphiphilic aggregates; liposomes; micelles; colloids; organic-inorganic nanoparticles; nanogels; surface functionalization; ruthenium-complex anticancer drugs; theranostic; drug-delivery nanocarriers; physico-chemical properties; light and neutron scattering techniques
Dr. Giuseppe Vitiello
E-Mail Website
Guest Editor
Dipartimento di Ingegneria Chimica, dei Materiali e della Produzione Industriale (DICMaPI), Università degli Studi di Napoli “Federico II”, Piazzale Tecchio 80, 80125 Napoli, Italy
Interests: nano(bio)materials synthesis; hybrid organic–inorganic nanostructures, amphiphile self-assembly; lipid aggregates; physico-chemical properties; structure–function relationships; structural defects and oxygen vacancies; reactive oxygen species (ROS) detection; spin-trapping; EPR spectroscopy; neutron scattering
Special Issues and Collections in MDPI journals

Special Issue Information

Dear Colleagues,

Nanocarriers have shown great opportunities in the field of targeted drug delivery, especially in cancer therapy. The functionalization of nanomaterials through the simultaneous assembly of chemical moieties has been a strategy of wide interest, to acquire properties such as longevity in circulation, site specificity, and stimuli sensitivity. Imparting multifunctionality to nanocarriers controls their biological interaction in a desired fashion and enhances the efficacy of therapy and diagnostic protocols. In this way, “simple nanocarriers” have attracted wide interest, and span diverse materials such as magnetic or colloidal metals, carbon-based structures, inorganic nanoparticles, liposomes, or polymeric formulations. These materials differ in size, shape, loading capacity, payload release, stability, retention, and clearance from the body, which impose further restrictions on their efficacy as therapeutic/diagnostic agents. Although nanocarrier technology has improved, their lack of target specificity limits their widespread use. Particularly, an increasing interest is focused on the design and formulation of complex multifunctional nanocarriers (i.e., nanohybrids; protocells; lipid-coated and/or polymeric-coated nanoparticles) combining multiple features of simple nanocarriers to exploit their strengths while reducing or eliminating their limitations. Indeed, they can show improved properties such as a high loading capacity, great stability, higher biocompatibility, reduced clearance, and increased targeting flexibility.

This Special Issue aims to attract contributions on all aspects of the chemistry, physico-chemistry, and biological activity of complex multifunctional organic and organic/inorganic nanocarriers. The challenge remains to further explore the range of their chemical and biophysico-chemical features, as well as their potential applications as biomedical (i.e., theranostic, diagnostic, anticancer, antibody, and antioxidant) nanosystems.

Prof. Luigi Paduano
Dr. Giuseppe Vitiello
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • multifunctional nanomaterials
  • complex nanocarriers
  • organic–inorganic nanoparticles
  • amphiphilic self-assembled nanostructures
  • hybrid nanomaterials
  • theranostic

Published Papers

This special issue is now open for submission.
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