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Contemporary Research Progress in Organofluorine Chemistry

A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Organic Chemistry".

Deadline for manuscript submissions: 30 June 2024 | Viewed by 1040

Special Issue Editors


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Guest Editor
The College of Chemistry, Nanchang University, Nanchang 330031, China
Interests: organic (Radio)fluoro chemistry; transition-metal catalysis; asymmetric synthesis; radical chemistry; halogenation

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Guest Editor
Key Laboratory of the Ministry of Education for Advanced Catalysis Materials, Department of Chemistry, Zhejiang Normal University, 688 Yingbin Road, Jinhua 321004, China
Interests: organofluorine chemistry; radical chemistry; asymettric catalysis; transition-metal catalysis

Special Issue Information

Dear Colleagues,

Organofluorine has received unprecedented attention due to its unique chemical and physical properties and biological activities. Fluorine-containing compounds have been proved to be of enormous value in the areas of pharmaceuticals, agrochemicals, and material science. As a result, there is growing interest in developing novel methods for the installation of fluorine and fluorine-containing functional groups in organic compounds. In line with this, significant progress has been achieved in developing novel strategies and fluorinated reagents, among them, fluorination, trifluoromethylation, difluoromethylation, perfluoroalkylation, trifluoromethoxylation trifluoromethylthioation and difluoromethylthioation, which have dominated in organofluorine chemistry.

Despite the recent progress in organofluorine chemistry, the field goes far behind the growing needs of both the industrial and academic community. In this Special Issue, we hope to gather the latest research trends in organofluorine chemistry, including the synthesis of fluorine-containing compounds and development of new methodologies. We welcome the submission of both original research papers and critical reviews on organofluorine chemistry. 

Prof. Dr. Xiaojun Zeng
Prof. Dr. Zuxiao Zhang
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • fluorination
  • trifluoromethylation
  • difluoromethylation
  • perfluoroalkylation
  • trifluoromethoxylation
  • trifluoromethylthioation
  • fluoroalkylation

Published Papers (1 paper)

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Research

12 pages, 4121 KiB  
Article
Practical Epoxidation of Olefins Using Air and Ubiquitous Iron-Based Fluorous Salen Complex
by Yamato Kato, Miho Kanoh, Hina Kobayashi, Takayuki Shioiri and Masato Matsugi
Molecules 2024, 29(5), 966; https://doi.org/10.3390/molecules29050966 - 22 Feb 2024
Viewed by 566
Abstract
The epoxidation of olefins by substituting “air” for potentially harmful oxidants was achieved using an oxidation method that integrated a fluorous iron(III) salen catalyst derived from common metals and pivalaldehyde. Several aromatic disubstituted olefins were converted into their corresponding epoxides with high efficiency [...] Read more.
The epoxidation of olefins by substituting “air” for potentially harmful oxidants was achieved using an oxidation method that integrated a fluorous iron(III) salen catalyst derived from common metals and pivalaldehyde. Several aromatic disubstituted olefins were converted into their corresponding epoxides with high efficiency and quantitative yields. This reaction represents an environmentally friendly oxidation process that utilizes an abundant source of air and employs a readily available metal, iron, in the form of salen complexes, making it an environmentally conscious oxidation reaction. Full article
(This article belongs to the Special Issue Contemporary Research Progress in Organofluorine Chemistry)
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