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Phytochemicals from Diet and Medicinal Plants: Chemical Diversity, Delivery Systems and Bioactivity

A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Natural Products Chemistry".

Deadline for manuscript submissions: 30 November 2024 | Viewed by 11793

Special Issue Editor

1. Department of Tea Science, Zhejiang University, Hangzhou 310058, China
2. Tea Research Institute, Zhejiang University, Hangzhou 310058, China
Interests: natural products; food functional ingredients; tea; bioactivity; health
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Phytochemicals from foods and medicinal plants possess various health benefits and fewer side effects compared with drugs, and thus have gained increasing attention in recent years. There have been several academic advances in this field with the discovery of new functions and mechanisms, metabolism and pharmacokinetics, chemical modification, green synthesis and delivery systems for increasing the stability and bioactivities of phytochemicals. These researches will be helpful for the extensive application of natural products in medicine, food, agriculture, daily chemical use and other fields.

This Special Issue welcomes original research and reviews on all aspects of phytochemicals from diet and medicinal plants, including but not limited to chemical structure, chemical modification and synthesis, extraction and isolation, determination methods, delivery systems, metabolism, bioactivities and application.

Dr. Bo Li
Guest Editor

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Keywords

  • phytochemicals
  • chemical structure
  • chemical modification
  • synthesis
  • delivery systems
  • bioactivities
  • metabolism

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Published Papers (3 papers)

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Research

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15 pages, 1315 KiB  
Article
Quantitative Study of Vitamin K in Plants by Pressurized Liquid Extraction and LC-MS/MS
by Iryna Bryshten, Łukasz Paprotny, Małgorzata Olszowy-Tomczyk and Dorota Wianowska
Molecules 2024, 29(18), 4420; https://doi.org/10.3390/molecules29184420 - 17 Sep 2024
Viewed by 448
Abstract
The health-promoting properties of vitamin K stimulate the growing interest in this compound, which translates into the development of new analytical methodologies for its determination. New, more efficient methods of its isolation are sought, paying increasingly more attention to the methods within currently [...] Read more.
The health-promoting properties of vitamin K stimulate the growing interest in this compound, which translates into the development of new analytical methodologies for its determination. New, more efficient methods of its isolation are sought, paying increasingly more attention to the methods within currently available extraction techniques that, owing to the optimization of the process, not only increase the extraction efficiency but are also economical and environmentally friendly. This article proposes a procedure for the extraction and analysis of one of the vitamin K vitamers, i.e., vitamin K1, using PLE and LC-MS/MS. It has been shown that the PLE technique can be optimized with a mathematical model—accelerating and reducing the costs of the extraction process—which, together with process automation, bodes well for industrial applications. The optimized process was used to extract vitamin K1 from various vegetables, showing very different contents of the test compound ranging from 1.22 to 114.30 µg/g dry weight for avocado and spinach, respectively. In addition, by showing the effect of water within the material subjected to extraction on the variable yield of vitamin K1, attention was drawn to the need to standardize the analytical methods used in assessing the quality of food products. Full article
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Review

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14 pages, 631 KiB  
Review
L-Theanine and Immunity: A Review
by Shuna Chen, Jiaxin Kang, Huanqing Zhu, Kaixi Wang, Ziyi Han, Leyu Wang, Junsheng Liu, Yuanyuan Wu, Puming He, Youying Tu and Bo Li
Molecules 2023, 28(9), 3846; https://doi.org/10.3390/molecules28093846 - 1 May 2023
Cited by 4 | Viewed by 8329
Abstract
L-theanine (N-ethyl-γ-glutamine) is the main amino acid in tea leaves. It not only contributes to tea flavor but also possesses several health benefits. Compared with its sedative and calming activities, the immunomodulatory effects of L-theanine have received less attention. Clinical and epidemiological studies [...] Read more.
L-theanine (N-ethyl-γ-glutamine) is the main amino acid in tea leaves. It not only contributes to tea flavor but also possesses several health benefits. Compared with its sedative and calming activities, the immunomodulatory effects of L-theanine have received less attention. Clinical and epidemiological studies have shown that L-theanine reduces immunosuppression caused by strenuous exercise and prevents colds and influenza by improving immunity. Numerous cell and animal studies have proven that theanine plays an immunoregulatory role in inflammation, nerve damage, the intestinal tract, and tumors by regulating γδT lymphocyte function, glutathione (GSH) synthesis, and the secretion of cytokines and neurotransmitters. In addition, theanine can be used as an immunomodulator in animal production. This article reviews the research progress of L-theanine on immunoregulation and related mechanisms, as well as its application in poultry and animal husbandry. It is hoped that this work will be beneficial to future related research. Full article
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11 pages, 4572 KiB  
Review
Quality Chemistry, Physiological Functions, and Health Benefits of Organic Acids from Tea (Camellia sinensis)
by Hongbo Chen, Fei Yu, Jiaxin Kang, Qiao Li, Hasitha Kalhari Warusawitharana and Bo Li
Molecules 2023, 28(5), 2339; https://doi.org/10.3390/molecules28052339 - 3 Mar 2023
Cited by 10 | Viewed by 2534
Abstract
Organic acids account for around 3% of the dry matter in tea leaves, and their composition and contents vary in different types of tea. They participate in the metabolism of tea plants, regulate nutrient absorption and growth, and contribute to the aroma and [...] Read more.
Organic acids account for around 3% of the dry matter in tea leaves, and their composition and contents vary in different types of tea. They participate in the metabolism of tea plants, regulate nutrient absorption and growth, and contribute to the aroma and taste quality of tea. Compared with other secondary metabolites in tea, the researches on organic acids are still limited. This article reviewed the research progresses of organic acids in tea, including analysis methods, the root secretion and physiological function, the composition of organic acids in tea leaves and related influencing factors, the contribution of organic acids to sensory quality, and the health benefits, such as antioxidation, promotion of digestion and absorption, acceleration of gastrointestinal transit, and regulation of intestinal flora. It is hoped to provide references for related research on organic acids from tea. Full article
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