Recent Advances in Oxidative Stress in Aging
A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Medicinal Chemistry".
Deadline for manuscript submissions: closed (31 July 2023) | Viewed by 2173
Special Issue Editor
Special Issue Information
Dear Colleagues,
Aging is the accumulation process of detrimental changes resulting from both genetic background and environmental exposition in the cells and tissues with advancing age. The free radical theory of aging offers the most accepted explanations for the aging process and related phenomena. The oxidative stress is defined as an imbalance between the production of reactive oxygen species (ROS) produced during normal metabolic reactions in a cell and the ability of the organism to neutralize or counteract ROS through the effects of antioxidants and detoxifying mechanisms. When the antioxidant defense of the body is overwhelmed, ROS cause oxidative damage to macromolecules, such as proteins, lipids, and nucleic acids.
In past, several polyphenols, endophytes, and flavonoids have been explored for their antioxidant and anti-aging activities through several methods, such as mice models, cell lines, and human volunteers. A significant number of studies have made use of nanotechnologies as carriers for these molecules. This Special Issue will focus on scientific studies involving the molecules that have antioxidant and anti-aging properties and the phytochemistry of their active groups, as well as pharmacological studies specifically.
The role of oxidative stress in human aging and associated diseases has been a long-debated research topic. After such extensive research, the actual mechanism of oxidative stress-induced aging has not been elucidated. Therefore, this Special Issue will attempt to gather information on the possible mechanisms involved in the role of oxidative stress in accelerating aging.
Prof. Dr. Pawan Kumar Maurya
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- aging
- oxidative stress
- phyto molecules
- polyphenols
- age-associated disorder
- flavonoids
