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Advances in Metallocene Chemistry

A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Organometallic Chemistry".

Deadline for manuscript submissions: 31 October 2025 | Viewed by 483

Special Issue Editor


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Guest Editor
Department of Chemistry, Ludwig-Maximilians-University Munich, Butenandtstr. 9, 81377 München, Germany
Interests: metallocene chemistry; coordination polymers; crystal structure determination
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Special Issue Information

Dear Colleagues,

Metallocenes are a class of unique organometallic compounds characterized by their “sandwich” structure, where a metal atom is surrounded by two cyclopentadienyl groups (Cp2M). The discovery and characterization of ferrocene, (η5-C5H5)2Fe, marked the beginning of a new era of organometallic chemistry. Back in the 1950s, it was discovered that variations in the structural motif “(η5-C5H5)2Fe” were not only possible by the introduction of ring substituents but also by exchanging iron with other metals; this is when the large family of (true) “metallocenes”, i.e., compounds of the type “Cp2M”, had come to life. Although not being “true” metallocenes, “half-sandwich compounds” with only one Cp ligand and “mixed sandwich complexes” with a transition metal sandwiched between two aromatic rings are often also called “metallocenes”. Research in metallocene chemistry spans not only basic chemistry but also extends into material science, catalysis, and bio-organometallic chemistry, among other interdisciplinary areas. This Special Issue, titled “Advances in Metallocene Chemistry”, aims to delve into the latest developments in metallocene chemistry, including the structure, chemical properties, synthetic methods, and applications of metallocenes across various fields.

This Special Issue will provide researchers with a comprehensive platform to share and discuss the latest research findings in metallocene chemistry, promoting scientific progress and technological innovation in this field. We look forward to your contributions and participation in advancing the development of metallocene chemistry together.

Prof. Dr. Karlheinz Sünkel
Guest Editor

Manuscript Submission Information

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Keywords

  • metallocene
  • macromolecular chemistry
  • bio-organometallic chemistry
  • catalysis

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Published Papers (1 paper)

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Review

69 pages, 16344 KiB  
Review
Enantiomerically Pure ansa-η5-Complexes of Transition Metals as an Effective Tool for Chirality Transfer
by Pavel V. Kovyazin, Leonard M. Khalilov and Lyudmila V. Parfenova
Molecules 2025, 30(12), 2511; https://doi.org/10.3390/molecules30122511 - 8 Jun 2025
Viewed by 316
Abstract
Chiral ansa-η5-complexes of transition metals have shown remarkable efficacy in organometallic synthesis and catalysis. Additionally, enantiomerically pure ansa-complexes hold promise for the development of novel chiral materials and pharmaceuticals. The discovery and synthesis of a diverse range of [...] Read more.
Chiral ansa-η5-complexes of transition metals have shown remarkable efficacy in organometallic synthesis and catalysis. Additionally, enantiomerically pure ansa-complexes hold promise for the development of novel chiral materials and pharmaceuticals. The discovery and synthesis of a diverse range of group IVB and IIIB metal complexes represents a significant milestone in the advancement of stereoselective catalytic methods for constructing metal-C, C-C, C-H, and C-heteroatom bonds. The synthesis of enantiomerically pure metallocenes can be accomplished through several strategies: utilizing optically active precursors of η5-ligands, separation of diastereomers of complexes with enantiomerically pure agents, and synthesis via the stereocontrolled reactions of enantiomerically pure σ-complexes with prochiral anions of η5-ligands. This review focuses on the analysis of various nuances of the synthesis of enantiomerically pure ansa-η5-complexes of titanium and lanthanum families. Their applicability as effective catalysts in asymmetric carbomagnesiation, carbo- and cycloalumination, oligo- and polymerization, Diels–Alder cycloaddition, reactions of zirconaaziridines, cyclization, hydrosilylation, hydrogenation, hydroamination, and other processes are highlighted as well. Full article
(This article belongs to the Special Issue Advances in Metallocene Chemistry)
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