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Synthesis and Applications of Antimicrobial Materials and Coatings

A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Materials Chemistry".

Deadline for manuscript submissions: 15 August 2024 | Viewed by 715

Special Issue Editors


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Guest Editor
Future Industries Institute, University of South Australia, Mawson Lakes, SA 5095, Australia
Interests: biomaterial developments and applications; surface functionalization; antibacterial coatings; plasma polymers; nanomaterials fabrication
Special Issues, Collections and Topics in MDPI journals

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Guest Editor Assistant
Biomedical Nanoengineering Laboratory, Flinders University, Adelaide, SA 5001, Australia
Interests: bacterial drug tolerance; antibiotic resistance; biofilm microbiology; biomaterial surface functionalization; nanomaterials

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Guest Editor Assistant
The College of Medicine and Public Health, Flinders University, Adelaide, Australia
Interests: biochemistry; biotechnology; cancer; cells; health/medicine; immunology; microbiology; microscopy; molecular biology
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Pathogenic microbes continue to present a seemingly insurmountable challenge to society. Not only do they threaten the health and lives of individuals, but their resilience also places considerable strain on healthcare systems, agriculture, water treatment systems, industry and the global economy. Further emphasizing this threat, antibiotic resistance continues to emerge and spread across the globe, and it can be said that humanity is hurtling towards a post-antibiotic era. In response to this challenge, researchers from diverse fields have dedicated decades to the development of innovative technologies and strategies to outsmart and conquer microbial pathogens. Despite their efforts, the threat has not abated; on the contrary, it continues to intensify.

Fortunately, progress marches on as researchers from various disciplines come together to tackle the challenge at hand with greater intensity. Multidisciplinary collaborative efforts have yielded new technologies that leverage advancements in fields such as nanoengineering, polymer chemistry, electrochemistry, molecular biology, microbiology and pharmacology, among others. By adopting interdisciplinary approaches such as these, society stands the best chance of avoiding the impending danger of a post-antibiotic era.

The purpose of this Special Issue is to showcase a compelling collection of primary research and review articles concerned with the latest fabrication methods and applications of antimicrobial materials and coatings, with a particular emphasis on interdisciplinary approaches. The overarching objective is to emphasize the potential strategies that can only arise through the collaborative efforts of diverse research fields. By doing so, it aims to inspire more cross-disciplinary collaborations that will expedite the research and development of antimicrobial technologies. The far-reaching benefits of such endeavors extend to all aspects of society.

Topics include, but are not limited to:

  • Synthesis of novel antimicrobial nanoparticles and other nanomaterials;
  • Delivery systems for antimicrobial agents;
  • Nanosystems for targeted delivery of antibacterial;
  • Materials with antifouling properties designed for applications in packaging and industrial sectors;
  • Smart and responsive materials and coatings that release antimicrobial compounds only in the presence of stimuli due to the presence of bacteria;
  • Fundamental insight into mechanisms of antimicrobial resistance;
  • Nanoparticles, materials and coatings that are effective against mature and established biofilms.

Prof. Dr. Krasimir Vasilev
Guest Editor

Dr. Andrew Hayles
Dr. Richard Bright
Guest Editor Assistants

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • antibacterial
  • nanomaterials
  • coatings
  • infections
  • drug delivery
  • antifouling
  • nanoparticles
  • nanostructures
  • bacteria

Published Papers (1 paper)

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Research

21 pages, 4145 KiB  
Article
Antimicrobial Composites Based on Methacrylic Acid–Methyl Methacrylate Electrospun Fibers Stabilized with Copper(II)
by Ana B. da Silva, Suelen P. Facchi, Fabricio M. Bezerra, Manuel J. Lis, Johny P. Monteiro, Elton. G. Bonafé, Adley F. Rubira and Alessandro F. Martins
Molecules 2024, 29(12), 2835; https://doi.org/10.3390/molecules29122835 - 14 Jun 2024
Viewed by 230
Abstract
This study presents fibers based on methacrylic acid–methyl methacrylate (Eudragit L100) as Cu(II) adsorbents, resulting in antimicrobial complexes. Eudragit L100, an anionic copolymer synthesized by radical polymerization, was electrospun in dimethylformamide (DMF) and ethanol (EtOH). The electrospinning process was optimized through a 2 [...] Read more.
This study presents fibers based on methacrylic acid–methyl methacrylate (Eudragit L100) as Cu(II) adsorbents, resulting in antimicrobial complexes. Eudragit L100, an anionic copolymer synthesized by radical polymerization, was electrospun in dimethylformamide (DMF) and ethanol (EtOH). The electrospinning process was optimized through a 22-factorial design, with independent variables (copolymer concentration and EtOH/DMF volume ratio) and three repetitions at the central point. The smallest average fiber diameter (259 ± 53 nm) was obtained at 14% w/v Eudragit L100 and 80/20 EtOH/DMF volume ratio. The fibers were characterized using scanning electron microscopy (SEM), infrared spectroscopy in attenuated total reflectance mode (FTIR-ATR), and differential scanning calorimetry (DSC). The pseudo-second-order mechanism explained the kinetic adsorption toward Cu(II). The fibers exhibited a maximum adsorption capacity (qe) of 43.70 mg/g. The DSC analysis confirmed the Cu(II) absorption, indicating complexation between metallic ions and copolymer networks. The complexed fibers showed a lower degree of swelling than the non-complexed fibers. The complexed fibers exhibited bacteriostatic activity against Gram-negative (Pseudomonas aeruginosa) and Gram-positive (Staphylococcus aureus) bacteria. This study successfully optimized the electrospinning process to produce thin fibers based on Eudragit L100 for potential applications as adsorbents for Cu(II) ions in aqueous media and for controlling bacterial growth. Full article
(This article belongs to the Special Issue Synthesis and Applications of Antimicrobial Materials and Coatings)
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