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Latest Review on Cyclizations and Ring-Opening Reactions in Organic Chemistry

A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Organic Chemistry".

Deadline for manuscript submissions: 31 October 2026 | Viewed by 115

Special Issue Editor


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Guest Editor
Department of Biomolecular Sciences, University of Urbino “Carlo Bo”, Urbino, PU, Italy
Interests: organic synthesis; heterocyclic chemistry; C-H activation; cyclization; michael addition; photochemistry
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Special Issue Information

Dear Colleagues,

The development of highly efficient synthetic protocols for the preparation of natural and non-natural compounds of medicinal interest, as well as key intermediates for functional materials, represents a major goal of contemporary organic chemistry.

This Special Issue, “Latest Review on Cyclizations and Ring-Opening Reactions in Organic Chemistry”, aims to showcase recent advances in cyclization and ring-opening methodologies, with a focus on mechanistic understanding and strategic applications. Topics of interest include pericyclic reactions, metal-catalyzed and organocatalytic cyclizations, radical and electrochemical/photochemical transformations, cascade and tandem processes, and asymmetric cyclization strategies. In addition, the Special Issue will cover innovative ring-opening reactions of strained carbocyclic and heterocyclic systems, including highly selective bond activation, stereocontrol, and sustainable reaction design. Contributions addressing unconventional activation modes, emerging reactivity concepts, and advanced synthetic strategies that increase molecular complexity are particularly encouraged. By bringing together critical and authoritative reviews from leading experts, this Special Issue aims to provide a comprehensive and up-to-date overview of the field, serving as both a valuable reference and a source of inspiration for future developments in cyclization and ring-opening chemistry for academic and industrial researchers.

Dr. Gianfranco Favi
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • annulation reaction
  • polar and radical cyclization
  • carbo and heterocyclic formation
  • ring-opening transformation
  • chemical bond formation and cleavage
  • complex molecular architectures

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Published Papers

This special issue is now open for submission.
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