Latest Review on Cyclizations and Ring-Opening Reactions in Organic Chemistry

Dear Colleagues,

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The development of highly efficient synthetic protocols for the preparation of natural and non-natural compounds of medicinal interest, as well as key intermediates for functional materials, represents a major goal of contemporary organic chemistry.

This Special Issue, “Latest Review on Cyclizations and Ring-Opening Reactions in Organic Chemistry”, aims to showcase recent advances in cyclization and ring-opening methodologies, with a focus on mechanistic understanding and strategic applications. Topics of interest include pericyclic reactions, metal-catalyzed and organocatalytic cyclizations, radical and electrochemical/photochemical transformations, cascade and tandem processes, and asymmetric cyclization strategies. In addition, the Special Issue will cover innovative ring-opening reactions of strained carbocyclic and heterocyclic systems, including highly selective bond activation, stereocontrol, and sustainable reaction design. Contributions addressing unconventional activation modes, emerging reactivity concepts, and advanced synthetic strategies that increase molecular complexity are particularly encouraged. By bringing together critical and authoritative reviews from leading experts, this Special Issue aims to provide a comprehensive and up-to-date overview of the field, serving as both a valuable reference and a source of inspiration for future developments in cyclization and ring-opening chemistry for academic and industrial researchers.

Dr. Gianfranco Favi
Guest Editor

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