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Novel Membranes and Coatings for Biomedical and Food Applications

A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Applied Chemistry".

Deadline for manuscript submissions: 31 July 2026 | Viewed by 4226

Special Issue Editor


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Guest Editor
Department of Interfacial Phenomena, Institute of Chemical Sciences, Faculty of Chemistry, Maria Curie-Skłodowska University, Maria Curie-Skłodowska Sq. 3, 20-031 Lublin, Poland
Interests: molecules at interfaces; lipids; peptides; biopolymers; nanostructure; intermolecular interactions; biomimetics

Special Issue Information

Dear Colleagues,

This Special Issue is devoted to biomimetic membranes and coatings that can be particularly beneficial for biomedical and food applications, including drug delivery, immunotherapy, and regenerative medicine, as well as food fortification and packaging. It covers the preparation and characterization of the newest generation of membranes and coatings that are being especially designed to allow the incorporation and/or controlled release of specific additives (minerals, vitamins, drugs, etc.); extracellular matrix imitation to promote cell adhesion, migration, and tissue regeneration; and food quality improvement in accordance with dietary recommendations for a healthy and balanced diet. The scope of the project includes the following: (1) physicochemical characteristics at the molecular level to elucidate how different components are arranged and distributed and interact with/within the membrane; (2) preparation of membrane-coated and membrane-based biomaterials; (3) determination of properties such as structural, wetting, antimicrobial, antioxidant, and sensory; (4) new advances in the incorporation/release of bioactive compounds and nutrients; (5) biocompatibility assessment; (6) optimization of coating methodology; and (7) design and development of biocompatible and edible coatings. Original research papers and reviews are welcome.

Prof. Dr. Jurak Małgorzata
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

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Keywords

  • model cell membranes
  • biocompatible and edible coatings
  • bioactive compounds
  • nutrients
  • biomaterials
  • surface characteristics
  • dispersion systems

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Published Papers (3 papers)

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Research

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23 pages, 1795 KB  
Article
Permeability of Phospholipid Membranes to Divalent Cations: The Effect of Pulsed Electric Field
by Małgorzata Jurak, Monika Sujka, Agnieszka Ewa Wiącek and Urszula Pankiewicz
Molecules 2026, 31(1), 151; https://doi.org/10.3390/molecules31010151 - 1 Jan 2026
Viewed by 783
Abstract
Achieving a high nutritional value of food often involves fortifying microorganisms (such as bacteria and yeast) used in baking and dairy industry with essential elements. The aim of this study was to investigate the effect of a pulsed electric field (PEF) on the [...] Read more.
Achieving a high nutritional value of food often involves fortifying microorganisms (such as bacteria and yeast) used in baking and dairy industry with essential elements. The aim of this study was to investigate the effect of a pulsed electric field (PEF) on the penetration and accumulation of Ca2+ and Mg2+ ions into model membranes of the food-grade yeast Saccharomyces cerevisiae. Simplified model membranes (monolayers and liposomes) were constructed using the phospholipid 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphatidylcholine (POPC). The Langmuir monolayer technique, dynamic light scattering (DLS) and microelectrophoresis were employed to characterize the physicochemical properties of the model membranes investigated. The results showed significant molecular-level differences in the interactions of the selected cations with lipid monolayers and bilayers in liposome structures. Both cations deeply penetrated the membrane’s hydrophilic region, yet two competing effects were evident: expansion induced by hydrated Mg2+ and condensation driven by Ca2+ bridging. Furthermore, the application of PEF increased the concentration of ions absorbed by the liposomes. Specifically, optimized PEF parameters resulted in cation accumulation within the model membranes, ranging from 6 to 13%. This finding correlates well with the increased Ca2+ and Mg2+ uptake observed in real yeast cells, providing a deeper understanding of the cell membrane-environment interface and the underlying processes. Full article
(This article belongs to the Special Issue Novel Membranes and Coatings for Biomedical and Food Applications)
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11 pages, 2809 KB  
Article
Utilization of All-Chitin Composite Films for High-Density Three-Dimensional Cell Cultivation
by Masayasu Totani, Mako Eda, Hiroyuki Shinchi and Jun-ichi Kadokawa
Molecules 2025, 30(21), 4243; https://doi.org/10.3390/molecules30214243 - 31 Oct 2025
Cited by 1 | Viewed by 772
Abstract
In this study, the potential of an all-chitin composite (AChC) film, prepared by dispersing and mixing high-crystalline scaled-down chitin nanofibers (SD-ChNFs) and low-crystalline chitin nanoparticles (ChNPs) in aqueous acetic acids, was evaluated for the formation of tissue-like cellular networks using a layered culture [...] Read more.
In this study, the potential of an all-chitin composite (AChC) film, prepared by dispersing and mixing high-crystalline scaled-down chitin nanofibers (SD-ChNFs) and low-crystalline chitin nanoparticles (ChNPs) in aqueous acetic acids, was evaluated for the formation of tissue-like cellular networks using a layered culture approach. The AChC film exhibited strong adhesion properties that enabled human cervical cancer (HeLa) cells to form a cellular network structure, whereas such adhesion and network formation were not observed with the individual components, SD-ChNFs and ChNPs. Furthermore, the cellular network structure was found to bridge the gaps between films, establishing three-dimensional (3D) connectivity. These findings demonstrate that AChC films serve as highly suitable functional biomaterials for constructing 3D tissue-like structures. Full article
(This article belongs to the Special Issue Novel Membranes and Coatings for Biomedical and Food Applications)
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Review

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26 pages, 4350 KB  
Review
Magnetic Nanoparticle-Based Nano-Packaging and Nano-Freezing in Food Storage Applications
by Sayan Ganguly and Shlomo Margel
Molecules 2025, 30(17), 3453; https://doi.org/10.3390/molecules30173453 - 22 Aug 2025
Cited by 1 | Viewed by 2271
Abstract
Magnetic nanoparticles (MNPs) have emerged as essential agents in food preservation, tackling significant issues related to shelf life extension, quality maintenance, and safety assurance. This thorough analysis consolidates current developments in MNP-based nano-packaging and nano-freezing technologies, emphasizing their processes, effectiveness, and commercial feasibility. [...] Read more.
Magnetic nanoparticles (MNPs) have emerged as essential agents in food preservation, tackling significant issues related to shelf life extension, quality maintenance, and safety assurance. This thorough analysis consolidates current developments in MNP-based nano-packaging and nano-freezing technologies, emphasizing their processes, effectiveness, and commercial feasibility. Metallic nanoparticles augment packaging efficacy via antibacterial properties, oxygen absorption, and real-time freshness assessment, while transforming freezing techniques by inhibiting ice crystal development and maintaining cellular integrity. Notwithstanding their potential applications, regulatory uncertainties, toxicity issues, and scalability challenges necessitate collaborative multidisciplinary approaches. We rigorously survey the technological, environmental, and safety aspects of MNP deployment in the food sector and suggest research priorities for sustainable implementation. Full article
(This article belongs to the Special Issue Novel Membranes and Coatings for Biomedical and Food Applications)
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