Innovative Analytical Approaches for the Isolation and Characterization of Drugs, Metabolites and Natural Bioactive Compounds
A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Analytical Chemistry".
Deadline for manuscript submissions: 30 June 2026 | Viewed by 20
Special Issue Editors
Interests: analytical chemistry; pharmaceutical analysis; proteomics; peptidomics; metabolomics; sample preparation; chromatography; HPLC; mass spectrometry; method development and optimization; bioanalysis; environmental analysis; green analytical chemistry; natural products; green extraction methods
Special Issues, Collections and Topics in MDPI journals
Interests: liquid chromatography; development of chromatographic analytical methods; pharmaceutical analysis; plant metabolomics; green chemistry; medicinal aromatic plants; illicit drugs; new psychoactive substances
Special Issue Information
Dear Colleagues,
From pharmaceuticals and metabolites to plant bioactive compounds, innovative analytical, separation, and isolation methods and protocols represent essential pathways toward future advancements in chemistry and life sciences. This Special Issue focuses on emerging analytical techniques and methodological innovations that contribute towards the isolation, identification, and quantification of drugs, metabolites, and natural bioactive compounds, improving our understanding of their bioactivity, pharmacokinetics, and metabolic profiles.
The objectives of this Special Issue are to promote novel separation, isolation, and analytical methodologies, highlight the applications of advanced analytical techniques (e.g., LC-MS, GC-MS, LC-MS/MS, GC-MS/MS, NMR, FT-IR), and encourage sustainable and green analytical workflows.
We invite the submission of original research papers and reviews focused on innovative methodologies for the extraction, isolation, characterization, and chemical analysis of drugs, metabolites, and natural bioactive compounds. Contributions that focus on innovative analytical protocols and green and sustainable methodologies are particularly encouraged to be submitted to this Special Issue.
This Special Issue invites articles focused on, but not limited to, the following topics:
- Green and sustainable methodologies for the separation and isolation of active ingredients and natural bioactive phytochemicals;
- Novel chromatographic methods for the determination of drugs, metabolites, and bioactive compounds;
- Ultrasound/microwave-assisted extraction protocols, supercritical CO2, and pressurized liquid extraction;
- Solvent-saving, miniaturized extraction protocols (e.g., solid-phase micro-extraction, microfluidic SPE) that boost the recovery of trace drugs, metabolites, and natural products in complex matrices;
- Metabolomic approaches for the discovery of biomarkers.
Dr. Evroula Hapeshi
Dr. Magda Psichoudaki
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- analytical chemistry
- chromatography
- extraction
- green chemistry
- bioactive compounds
- drugs
- metabolites
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