Special Issue "Oral Biofilms"
Deadline for manuscript submissions: 30 November 2019
Prof. Dr. Zvi Loewy
Touro College of Pharmacy, The Touro College and University System, New York, NY 10027, USA
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Interests: Oral and systemic health: The link between oral infection and various respiratory diseases in the dentate population has been the focus of several studies. The increased presence of respiratory pathogens on natural dentition is associated with chronic obstructive pulmonary disease (COPD). Data from the Loewy Laboratory have demonstrated a significant association between COPD and edentulism; an association greater than that of the dentate population. Our lab is focused on characterizing the oral microbiome in both the dentate and the edentulous populations
Microbial species are present in nature either as planktonic cells or incorporated into biofilms. Biofilms evolve from the planktonic state and are characterized as dense micro-communities that grow on inert surfaces and encapsulate themselves with secreted polymers. When organisms form a biofilm, they are able to adapt to environmental change by altering their gene expression patterns. The biofilm structure and corresponding change in gene expression can protect the microbes from disinfectant agents or antibiotics. The resultant biofilm can pose a serious public health issue. The physical nature of biofilms and the survival mechanisms they possess, whether phenotypic adaptability or genetic resistance, leave them impervious to antibiotic treatment. Given the lack of response to traditional antimicrobial therapy, biofilm infections currently pose a great challenge to the world of medicine.
The majority of the oral microbes are commensal organisms. Those that are pathogenic microbes can result in oral infections and at times initiate systemic diseases. This Special Issue focused on oral biofilms will address: (1). The development and life cycle of oral biofilms; (2). innovative approaches to study oral biofilms; and (3). methods to control the pathogenesis associated with biofilms.
Prof. Dr. Zvi Loewy
Manuscript Submission Information
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