Special Issue "Microbial Degradation of Xenobiotics"

A special issue of Microorganisms (ISSN 2076-2607). This special issue belongs to the section "Environmental Microbiology".

Deadline for manuscript submissions: 30 September 2019

Special Issue Editor

Guest Editor
Prof. Dr. Yuji Nagata

Department of Environmental Life Sciences, Graduate School of Life Sciences, Tohoku University, Sendai 980-8577, Japan
Website | E-Mail
Interests: microbial degradation of environmental pollutants; evolution and adaptation of bacteria, protein evolution; mobile genetic elements; bacterial genome and metagenome

Special Issue Information

Dear Colleagues,

Xenobiotics have been released into the environment by human activities, and they often cause environmental pollution problems, since most such compounds cannot be readily degraded and have harmful effects on the natural ecosystem, including human beings. However, some microorganisms have been isolated that degrade man-made xenobiotics. Especially, most aerobic xenobiotic-degrading bacterial strains can use such chemicals as their sole sources of carbon and energy, and thus they are excellent models for studying the adaptation and evolution of bacteria in the environment.

Recent genome analyses of the bacterial strains degrading xenobiotics have strongly suggested that they indeed emerged relatively recently by gathering genes for the degradation of xenobiotics, and mobile genetic elements played important roles in the recruitment of the genes. However, the origin of the genes and the evolutionary processes of such bacterial strains remain largely unknown. Ongoing comprehensive genome and metagenome analyses may provide some insights into such mysteries, and the genes for the degradation of xenobiotics can be used as probes to reveal novel mechanisms for the evolution of microorganisms. In addition, enzymes for the degradation of xenobiotics are good materials for studies of protein evolution, since generally they show promiscuous activity and their properties change dramatically with a small number of mutations. On the other hand, the importance of microbial consortia and symbiosis for the degradation of xenobiotics in the environment has also been suggested, and thus studies of xenobiotic degradation may provide some novel concepts into the field of microbial ecology.

For this Special Issue of Microorganisms, we invite you to send contributions encompassing any aspects relating to the evolution and adaptation of microorganisms towards xenobiotics.

Prof. Dr. Yuji Nagata
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Microorganisms is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • biodegradation
  • xenobiotics
  • environmental pollutants
  • evolution and adaptation
  • genome and metagenome
  • mobile genetic elements
  • protein evolution
  • microbial consortia
  • symbiosis

Published Papers

This special issue is now open for submission.
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