Special Issue "Gut Microbiota and Gastroenterology"
Deadline for manuscript submissions: closed (31 December 2021) | Viewed by 4504
2. Chief of the Center for Diagnosis and Treatment of Digestive Diseases, CEMAD, Gastroenterology Department, Fondazione Policlinico Gemelli, IRCCS, 00168 Rome, Italy
Interests: digestive diseases; inflammatory bowel diseases; digestive cancer; gut microbiota, internal medicine
Special Issues, Collections and Topics in MDPI journals
The gastrointestinal tract is inhabited by trillions of microorganisms, such as bacteria, viruses, and fungi which cooperate with each other to generate a complex organ called gut microbiota. Therefore, the balance between the various microbial species is fundamental for maintaining health, both gastrointestinal and not. Indeed, gut microbiota is involved in maintaining the regular functioning of intestinal barrier, in the development of the immune system and others.
Several factors, such as diet, lifestyle, and drugs (mainly antibiotics), can alter the physiological balance between microbial species. The disruption of “healthy” microbiota promotes the development of several diseases.
The role of microbes in various gastrointestinal diseases has been hypothesized since the last century. However, only in the last few decades, thanks to the development of metagenomic sequencing techniques and proteomics studies, has it been possible to identify specific correlations between microbial alterations and gastrointestinal disease. To date, a slew of evidence is available mainly for disorders of the bowel or colon, but also for stomach, liver, and pancreas diseases. Even more important are the therapeutic perspectives that will continue to be obtained from the modulation of the microbiota, in particular with antibiotics, probiotics or fecal microbiota transplantation.
The aim of this Special Issue is to report recent evidence on the role of the gut microbiota in gastrointestinal diseases, focusing on the critical analysis on the pathophysiological role and on therapeutic perspectives.
Prof. Antonio Gasbarrini
Manuscript Submission Information
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- Gut microbiota
- Fecal microbiota transplantation
- H. pylori
- Celiac disease
- C. difficile
- Inflammatory bowel disease (IBD)
- Irritable bowel syndrome (IBS)
- Colon cancer
- Non alcoholic fatty liver disease (NAFLD)
- Chronic hepatitis