Sensors and Actuators for Organoids and Organ Chips
A special issue of Micromachines (ISSN 2072-666X). This special issue belongs to the section "E：Engineering and Technology".
Deadline for manuscript submissions: closed (31 August 2021) | Viewed by 401
Special Issue Editor
Special Issue Information
Dear Colleagues,
Organoids and organ-on-a-chip devices have enabled inquiries into biological processes that could not be observed previously. Organoids are cell co-cultures that grow to mimic certain functions of an organ, while organ-on-a-chip devices integrate cells within engineered tools (microfluidics) to capture cellular interactions. Examples include, but are not limited to, gut organoids and blood-brain barrier microfluidic chips. Each tool provides a complementary method to interrogate the biology under investigation in three dimensions by controlling the composition and micro-environment of the organ-like device. As a consequence, significant progress has been made in engineering the properties of individual and serial organotypic systems. Because these systems can be integrated with engineering equipment, they provide the opportunity to collect data that cannot be measured in-vivo. However, this relies on the adoption and advancement of sensors and actuators to probe and manipulate cells and reagents within these systems. This Special Issue is dedicated to the progress in integrating sensors and actuators into organoids and organ-on-a-chip devices, so that real-time measurements of their biological properties may be performed. You are invited to contribute your work to this Special Issue for consideration. We look forward to receiving your submission.
Dr. C. Ryan Oliver
Guest Editor
Manuscript Submission Information
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Keywords
- organ-on-a-chip
- organoids
- sensors
- actuators
- pumps
- in-situ
- in-vitro
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