Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
5.2
3.0
Journals
Micromachines
Special Issues
Micro-Devices for Pathogen Detection
share announcement

Micro-Devices for Pathogen Detection

A special issue of Micromachines (ISSN 2072-666X). This special issue belongs to the section "B：Biology and Biomedicine".

Deadline for manuscript submissions: closed (15 September 2021) | Viewed by 3012

Special Issue Editor

Dr. Wenwen Jing

E-Mail Website
Guest Editor
Department of Medical Microbiology and Parasitology, Shanghai Medical College of Fudan University, Shanghai 200032, China
Interests: microfluidics; digital immunoassay; biomarker rapid detection; nucleic acid analysis; single molecule detection

Special Issue Information

Dear Colleagues,

Epidemics caused by infectious diseases, such as the COVID-19 outbreak at the end of 2019, represent unprecedented challenges for mankind. When facing unknown infectious diseases, it is important to identify pathogens quickly and effectively, so as not to cause public panic. Although the performance of current clinical and laboratory testing instruments is rapidly improving, there is still an urgent need for the development of micro-devices that can simultaneously achieve detection sensitivity, speed, portability, and accuracy. Gene sequencing, protein analysis, nucleic acid analysis, and culture-based instruments are still the most commonly used methods for pathogen identification and detection. Some culture-free detection techniques have also been reported. However, there are currently no related devices available on the market.

In the past decade, the development of new detection devices that are based on optics, electrochemistry, analytical chemistry, microscopic imaging technology, 2D materials, micro-electro-mechanical systems (MEMS) manufacturing, and computer analysis has gradually gained momentum in the field of pathogen detection. Therefore, this Special Issue aims to introduce research papers, newsletters, and review articles focusing on the development of new micro-devices aimed at the detection of pathogens (such as bacteria, viruses, fungi, parasites, and so on).

We also welcome papers that described novel designs or fabrications that have potential applications as one of the modules of micromachines related to pathogen detection. These modules can be applied hopefully to pathogen detection in the future, although so far no biological experiments have been conducted to verify its feasibility, there is enough other experimental evidence to prove it is reliable and usable.

We look forward to receiving your submissions.

Dr. Wenwen Jing
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Micromachines is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2100 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • micro-devices for pathogen identification and detection
  • micro-devices for rapid diagnosis of infectious diseases
  • micro-devices for highly sensitive analysis of pathogens
  • micro-devices for rapid analysis of the genes and proteins of pathogens
  • culture-free analysis micro-devices
  • microfluidics
  • MEMS

Benefits of Publishing in a Special Issue

  • Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
  • Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
  • Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
  • External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
  • e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.

Further information on MDPI's Special Issue policies can be found here.

Published Papers (1 paper)

Order results
Result details
Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:

Research

13 pages, 6484 KiB  
Article
A Three-Dimensional Micromixer Using Oblique Embedded Ridges
by Lin Li, Qingde Chen, Guodong Sui, Jing Qian, Chi-Tay Tsai, Xunjia Cheng and Wenwen Jing
Micromachines 2021, 12(7), 806; https://doi.org/10.3390/mi12070806 - 8 Jul 2021
Cited by 3 | Viewed by 2374
Abstract
A micromixer is one of the most significant components in a microfluidic system. A three-dimensional micromixer was developed with advantages of high efficiency, simple fabrication, easy integration, and ease of mass production. The designed principle is based on the concepts of splitting–recombination and [...] Read more.
A micromixer is one of the most significant components in a microfluidic system. A three-dimensional micromixer was developed with advantages of high efficiency, simple fabrication, easy integration, and ease of mass production. The designed principle is based on the concepts of splitting–recombination and chaotic advection. A numerical model of this micromixer was established to characterize the mixing performance for different parameters. A critical Reynolds number (Re) was obtained from the simulation results. When the Re number is smaller than the critical value, the fluid mixing is mainly dependent on the mechanism of splitting–recombination, therefore, the length of the channel capable of complete mixing (complete mixing length) increases as the Re number increases. When the Re number is larger than the critical value, the fluid mixing is dominated by chaotic advection, and the complete mixing length decreases as the Re number increases. For normal fluids, a complete mixing length of 500 µm can be achieved at a very small Re number of 0.007 and increases to 2400 µm as the Re number increases to the critical value of 4.7. As the Re number keep increasing and passes the critical Re number, the complete mixing length continues to descend to 650 µm at the Re number of 66.7. For hard-to-mix fluids (generally referring to fluids with high viscosity and low diffusion coefficient, which are difficult to mix), even though no evidence of strong chaotic advection is presented in the simulation, the micromixer can still achieve a complete mixing length of 2550 µm. The mixing performance of the micromixer was also verified by experiments. The experimental results showed a consistent trend with the numerical simulation results, which both climb upward when the Re number is around 0.007 (flow rate of 0.03 μm/min) to around 10 (flow rate of 50 μm/min), then descend when the Re number is around 13.3 (flow rate of 60 µm/min). Full article
(This article belongs to the Special Issue Micro-Devices for Pathogen Detection)
►▼ Show Figures

Figure 1

Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:
 
Displaying articles 1-1
Back to TopTop