Special Issue "Acoustofluidics in Medicine and Biology"
Deadline for manuscript submissions: closed (28 February 2018)
Dr. Dario Carugo
Faculty of Engineering and the Environment, University of Southampton, Southampton SO17 1BJ, UK
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Interests: bio-microfluidics; biomedical microdevices; acoustofluidics; drug delivery; biomedical ultrasound; ultrasound bio-effects; nano- & micro-particles; interventional medicine; physiological models
The development of many acoustofluidic devices has focussed on medical or biological applications, largely because acoustofluidic techniques are well-suited for handling cell sized bodies, from micron-sized bacteria to larger mammalian cells. In addition, acoustic traps can work effectively at energy densities that are compatible with cell survival, the acoustic fields are relatively robust to different cell media, and traps can work over large distances. The majority of reported acoustofluidic cell-manipulation applications are in flow-through devices for sample preparation, detection and diagnosis, with obvious relevance for microfluidic point-of-care approaches. There is also an interest in using traps for static holding of cells and for bringing cells together in a controlled way for applications, such as toxicology testing, drug discovery, tissue engineering, and the study of cell–cell interactions. The acoustic field can mechanically stimulate biological cells to deliver bioactive compounds, to elicit a biological response, or to investigate ultrasound–cell interaction mechanisms.
There remain significant challenges to wider uptake of the technology however, including increasing throughput in flow-through devices, improving device reliability, system integration, refining the stability of trapped cells, and understanding the response of different cell types to the acoustofluidic environment. This Special Issue will comprise original research articles, reviews and short communications that describe recent advances in the field, to include new biomedical applications, addressing of fundamental biological and physical issues, and improving device and system design and implementation.
Prof. Martyn Hill
Dr. Dario Carugo
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Micromachines is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- lab on a chip
- medical diagnostics
- tissue engineering
- point of care devices
- cell handling