Micro- and Nano-Technologies for the Application of Nanocarriers as Theranostics
A special issue of Micromachines (ISSN 2072-666X). This special issue belongs to the section "B：Biology and Biomedicine".
Deadline for manuscript submissions: closed (20 November 2021) | Viewed by 3223
Special Issue Editor
Interests: biophotonics; raman spectroscopy; extracellular vesicles; regenerative medicine; biosensor; SPR; nanomedicine; biomarkers; point of care
Special Issue Information
Dear Colleagues,
In the fields of diagnostics and drug delivery, nanosized carriers of endogenous and exogenous bioactive molecules are emerging as valuable tools in precision medicine, being considered theranostics, i.e., nanocarriers with therapeutic functionalities, but also vehicles of biomarkers for diagnostic and prognostic application to personalize the therapeutic intervention. Among the proposed tools, natural nanoparticles, i.e., extracellular vesicles, have also been proposed as cargoes for proteins, lipids and oligonucleotides from the parental cell. New perspectives in nanocarrier-assisted therapeutics clinical application derive from cutting-edge, technologically advanced solutions that can overcome limits in the reproducibility and reliability of the proposed protocols. In the case of extracellular vesicles, some of the problems related to partial purification, limited resolution and poor yield are limiting their use. In the field of regenerative medicine and regenerative rehabilitation, nanoparticles and nanocarriers, including extracellular vesicles released by stem cells, have demonstrated their ability to foster recovery and repair of damaged and aged tissues, but application methods and efficacy are debated mainly because of technical challenges.
This Special Issue will focus on recent advances in the field of nanocarrier-assisted therapeutics and extracellular vesicles. Specific areas of interest include—but are not limited to—advanced methodologies for the use of nanocarriers and extracellular vesicles for diagnostic and drug delivery, biosensors and innovative techniques for the detection of EVs as biomarkers for precision medicine, the application of EVs and other nanocarriers in tissue regeneration and regenerative rehabilitation. Particular interest is dedicated to development of new devices, including optical imaging, spectroscopy and spectrometry, coupled with artificial intelligence for the use of nanocarriers as therapeutic and diagnostic tools.
Dr. Alice Gualerzi
Guest Editor
Manuscript Submission Information
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Keywords
- theranostics
- nanocarrier-assisted therapeutics
- extracellular vesicles
- nanoparticles
- nanotechnologies
- precision medicine
- regenerative medicine
- sensors
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