Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
4.7
3.4
Journals
Micromachines
Special Issues
Microfluidics for Cell Detection and Sorting
share announcement

Microfluidics for Cell Detection and Sorting

A special issue of Micromachines (ISSN 2072-666X). This special issue belongs to the section "B：Biology and Biomedicine".

Deadline for manuscript submissions: closed (1 March 2021) | Viewed by 8235

Special Issue Editor

Dr. Muhsincan Sesen

E-Mail Website
Guest Editor
Department of Bioengineeering, Imperial College London, London SW7 2AZ, UK
Interests: microfluidics; droplet microfluidics; detection; sorting; surface acoustic waves; imaging; raman spectroscopy
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Recent advances in microfluidic cell detection and sorting techniques have enabled biologists to gain invaluable insight into biological functions associated with cell heterogeneity. Applications of these techniques include cancer research, directed evolution studies, environmental sampling, personalised medicine, drinking water monitoring and more. Even though there are powerful cell detection and sorting techniques, such as fluorescence-activated cell sorting (FACS) and magnetic-activated cell sorting (MACS), they have their limitations. Therefore, there is a strong need for specialised cell detection and sorting techniques.

Lately, it has become significantly harder to communicate pure engineering studies in this field. Such studies may include reporting a new on-chip detection technique or describing a novel sorting technique with advantages over its counterparts. This Special Issue aims to collate such studies to disseminate this research and attract wider attention. You are cordially invited to submit research papers, short communications, and review articles to this Special Issue in Micromachines titled “Microfluidics for Cell Detection and Sorting”.

Dr. Muhsincan Sesen
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Micromachines is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • Microfluidics
  • Cell Detection
  • Cell Sorting
  • Lab-on-a-Chip
  • Droplet Microfluidics
  • Label-Free

Published Papers (2 papers)

Download All Papers
Order results
Result details
Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:

Research

12 pages, 4650 KiB  
Communication
Extremely High-Throughput Parallel Microfluidic Vortex-Actuated Cell Sorting
by Alex A. Zhukov, Robyn H. Pritchard, Mick J. Withers, Tony Hailes, Richard D. Gold, Calum Hayes, Mette F. la Cour, Fred Hussein and Salman Samson Rogers
Micromachines 2021, 12(4), 389; https://doi.org/10.3390/mi12040389 - 02 Apr 2021
Cited by 6 | Viewed by 3969
Abstract
We demonstrate extremely high-throughput microfluidic cell sorting by making a parallel version of the vortex-actuated cell sorter (VACS). The set-up includes a parallel microfluidic sorter chip and parallel cytometry instrumentation: optics, electronics and control software. The result is capable of sorting lymphocyte-sized particles [...] Read more.
We demonstrate extremely high-throughput microfluidic cell sorting by making a parallel version of the vortex-actuated cell sorter (VACS). The set-up includes a parallel microfluidic sorter chip and parallel cytometry instrumentation: optics, electronics and control software. The result is capable of sorting lymphocyte-sized particles at 16 times the rate of our single-stream VACS devices, and approximately 10 times the rate of commercial cell sorters for an equivalent procedure. We believe this opens the potential to scale cell sorting for applications requiring the processing of much greater cell numbers than currently possible with conventional cell sorting. Full article
(This article belongs to the Special Issue Microfluidics for Cell Detection and Sorting)
►▼ Show Figures

Figure 1

16 pages, 7134 KiB  
Article
Optical Investigation of Individual Red Blood Cells for Determining Cell Count and Cellular Hemoglobin Concentration in a Microfluidic Channel
by Ann-Kathrin Reichenwallner, Esma Vurmaz, Kristina Battis, Laura Handl, Helin Üstün, Tivadar Mach, Gabriele Hörnig, Jan Lipfert and Lukas Richter
Micromachines 2021, 12(4), 358; https://doi.org/10.3390/mi12040358 - 26 Mar 2021
Cited by 4 | Viewed by 3716
Abstract
We demonstrate a blood analysis routine by observing red blood cells through light and digital holographic microscopy in a microfluidic channel. With this setup a determination of red blood cell (RBC) concentration, the mean corpuscular volume (MCV), and corpuscular hemoglobin concentration mean (CHCM) [...] Read more.
We demonstrate a blood analysis routine by observing red blood cells through light and digital holographic microscopy in a microfluidic channel. With this setup a determination of red blood cell (RBC) concentration, the mean corpuscular volume (MCV), and corpuscular hemoglobin concentration mean (CHCM) is feasible. Cell count variations in between measurements differed by 2.47% with a deviation of −0.26×106 μL to the reference value obtained from the Siemens ADVIA 2120i. Measured MCV values varied by 2.25% and CHCM values by 3.78% compared to the reference ADVIA measurement. Our results suggest that the combination of optical analysis with microfluidics handling provides a promising new approach to red blood cell counts. Full article
(This article belongs to the Special Issue Microfluidics for Cell Detection and Sorting)
►▼ Show Figures

Figure 1

Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:
 
Displaying articles 1-2
Back to TopTop