Advanced Polymers and Biodegradable Mg Materials in Biomedical Microfluidic Systems: Innovations in Etching, Bonding and Nanotechnology Applications

A special issue of Micromachines (ISSN 2072-666X). This special issue belongs to the section "B:Biology and Biomedicine".

Deadline for manuscript submissions: 30 November 2024 | Viewed by 1206

Special Issue Editors


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Guest Editor
Department of Mechanical Engineering, National Taiwan University of Science and Technology, Taipei 106, Taiwan
Interests: bio-MEMS; tribology; wear; metal matrix composite materials; magnesium alloy; hydrogen storage materials; metallic materials for microbial fuel cell
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Guest Editor Assistant
Department of Mechanical Engineering, National Taiwan University of Science and Technology, Taipei 106, Taiwan
Interests: semiconductor wafer bonding science and technology; silicon photonic laser technology; electrochemical; bio-MEMS device for silicon-based materials; high-pressure die casting technique for automotive engines; thin-film solar cells
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

This comprehensive overview covers innovations in etching techniques, bonding processes, and nanotechnology applications, providing insights into the latest advancements. By delving into the unique properties and capabilities of advanced polymer and biodegradable Mg materials, this work highlights their potential to revolutionize the design and functionality of microfluidic devices in biomedical applications. Furthermore, it examines the integration of advanced polymer and biodegradable Mg materials in the development of miniaturized mechanical components, exploring the synergy between these materials and MEMS technology. In particular, biodegradable Mg materials are biocompatible and can naturally degrade in the body, making them ideal for use in temporary or implantable devices. This work sheds light on the potential for further innovations and breakthroughs in the design and fabrication of microscale devices with enhanced performance and functionality through the integration of advanced polymers and biodegradable Mg materials.

This Special Issue offers a platform to share knowledge, network, and build relationships among scholars, presenting and discussing topics such as (but not limited to):

  • Advanced Polymer Materials in Biomedical Microfluidics;
  • Innovations in Etching Techniques;
  • Bonding Processes and Techniques in Microfluidic Devices;
  • Nanotechnology Applications in Biomedical Devices;
  • Integration of Advanced Polymer Materials in MEMS;
  • Synergy between Polymer Materials and MEMS Technology;
  • The Relationship between the Structure, Properties, and Performance of Microscale Devices;
  • Biodegradable Mg materials and Devices.

Prof. Dr. Song-Jeng Huang
Guest Editor

Dr. Chao-Ching Chiang
Guest Editor Assistant

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Keywords

  • polymer materials
  • biomedical microfluidics
  • etching techniques
  • bonding processes 
  • biodegradable Mg materials 

Published Papers (1 paper)

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Research

13 pages, 3227 KiB  
Article
Using a 3D Silicon Micro-Channel Device and Raman Spectroscopy for the Analysis of Whole Blood and Abnormal Blood
by Chao-Ching Chiang, Song-Jeng Huang, Philip Nathaniel Immanuel, Jun-Han Lan, Fang-Yuh Lo and Kung-Chia Young
Micromachines 2024, 15(1), 21; https://doi.org/10.3390/mi15010021 - 22 Dec 2023
Cited by 1 | Viewed by 951
Abstract
Blood testing is a crucial application in the field of clinical studies for disease diagnosis and screening, biomarker discovery, organ function assessment, and the personalization of medication. Therefore, it is of the utmost importance to collect precise data in a short time. In [...] Read more.
Blood testing is a crucial application in the field of clinical studies for disease diagnosis and screening, biomarker discovery, organ function assessment, and the personalization of medication. Therefore, it is of the utmost importance to collect precise data in a short time. In this study, we utilized Raman spectroscopy to analyze blood samples for the extraction of comprehensive biological information, including the primary components and compositions present in the blood. Short-wavelength (532 nm green light) Raman scattering spectroscopy was applied for the analysis of the blood samples, plasma, and serum for detection of the biological characteristics in each sample type. Our results indicated that the whole blood had a high hemoglobin content, which suggests that hemoglobin is a major component of blood. The characteristic Raman peaks of hemoglobin were observed at 690, 989, 1015, 1182, 1233, 1315, and 1562–1649 cm−1. Analysis of the plasma and serum samples indicated the presence of β-carotene, which exhibited characteristic peaks at 1013, 1172, and 1526 cm−1. This novel 3D silicon micro-channel device technology holds immense potential in the field of medical blood testing. It can serve as the basis for the detection of various diseases and biomarkers, providing real-time data to help medical professionals and patients better understand their health conditions. Changes in biological data collected in this manner could potentially be used for clinical diagnosis. Full article
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