Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
5.2
3.0
Journals
Micromachines
Special Issues
Advanced Micromixing Technology
share announcement

Advanced Micromixing Technology

A special issue of Micromachines (ISSN 2072-666X). This special issue belongs to the section "A：Physics".

Deadline for manuscript submissions: 30 November 2025 | Viewed by 1755

Special Issue Editor

Dr. Lanju Mei

E-Mail Website
Guest Editor
Department of Engineering and Aviation Sciences, University of Maryland Eastern Shore, Princess Anne, MD 21853, USA
Interests: microfluidics; non-Newtonian microfluid; electrokinetics
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Microfluidics has attracted increasing attention with its significant applications for biological and medical processes such as chemical synthesis, disease diagnosis, drug delivery, and genetic analysis. Mixing of species in microfluidics plays an important role in many of these applications. Due to low Reynold Numbers, the fluid mixing is limited to diffusion, leading to difficulties in achieving rapid and efficient mixing of fluids in microchannels. The mixing efficiency can directly affect the performance of the whole microfluidic system. Researchers have employed different techniques to enhance the mixing efficiency of microfluidic devices, classified as passive (obstacles, serpentine, lamination and spiral structures, etc.) and active (acoustic, electric, pressure, magnetic field, etc.) micromixers.

In this Special Issue, we welcome research papers and review articles related to the applications, fundamentals, novel design, experiments, and analysis of micromixing technology.

Dr. Lanju Mei
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Micromachines is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2100 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • microfluidic mixing
  • mixing efficiency
  • passive micromixer
  • active micromixer
  • acoustic, electric, pressure, magnetic field, etc.
  • micromixing technology
  • obstacles, serpentine, lamination and spiral structures, etc.

Benefits of Publishing in a Special Issue

  • Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
  • Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
  • Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
  • External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
  • e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.

Further information on MDPI's Special Issue policies can be found here.

Published Papers (3 papers)

Download All Papers
Order results
Result details
Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:

Research

10 pages, 1937 KiB  
Article
Fabrication of a Spiral Microfluidic Chip for the Mass Production of Lipid Nanoparticles Using Laser Engraving
by Inseong Choi, Mincheol Cho, Minseo Song, Byeong Wook Ryu, Bo Mi Kang, Joonyeong Kim, Tae-Kyung Ryu and Sung-Wook Choi
Micromachines 2025, 16(5), 501; https://doi.org/10.3390/mi16050501 - 25 Apr 2025
Viewed by 200
Abstract
A spiral microfluidic chip (SMC) and multi-spiral microfluidic chip (MSMC) for lipid nanoparticle (LNP) production were fabricated using a CO2 laser engraving method, using perfluoropolyether (PFPE) and poly(ethylene glycol) diacrylate as photopolymerizable base materials. The SMC includes a spiral microchannel that enables [...] Read more.
A spiral microfluidic chip (SMC) and multi-spiral microfluidic chip (MSMC) for lipid nanoparticle (LNP) production were fabricated using a CO2 laser engraving method, using perfluoropolyether (PFPE) and poly(ethylene glycol) diacrylate as photopolymerizable base materials. The SMC includes a spiral microchannel that enables rapid fluid mixing, thereby facilitating the production of small and uniform LNPs with a size of 72.82 ± 24.14 nm and a PDI of 0.111 ± 0.011. The MSMC integrates multiple parallel SMC structures, which enables high-throughput LNP production without compromising quality and achieves a maximum production capacity of 960 mL per hour. The LNP fabrication technology using SMC and MSMC has potential applications in the pharmaceutical field due to the ease of chip fabrication, the simplicity and cost-effectiveness of the process, and the ability to produce high-quality LNPs. Full article
(This article belongs to the Special Issue Advanced Micromixing Technology)
►▼ Show Figures

Figure 1

19 pages, 5043 KiB  
Article
Enhanced Mixing in Microflow Systems Using Magnetic Fields—Experimental and Numerical Analyses
by Marek Wojnicki, Xuegeng Yang, Piotr Zabinski and Gerd Mutschke
Micromachines 2025, 16(4), 422; https://doi.org/10.3390/mi16040422 - 31 Mar 2025
Viewed by 315
Abstract
This study presents both numerical and experimental analyses of enhanced mixing in a microflow system under the influence of a magnetic field. The research employed COMSOL Multiphysics for numerical simulations and Particle Image Velocimetry (PIV) for experimental validation. In the experimental microfluidic setup, [...] Read more.
This study presents both numerical and experimental analyses of enhanced mixing in a microflow system under the influence of a magnetic field. The research employed COMSOL Multiphysics for numerical simulations and Particle Image Velocimetry (PIV) for experimental validation. In the experimental microfluidic setup, permanent neodymium magnets were used to influence a laminar flow of water partially enriched with Ho(III) ions using the magnetic field. The findings confirmed that the strong interaction between Ho(III) ions and the magnetic field significantly affected the flow and may have resulted in vortex shedding downstream of the region with the highest magnetic field intensity. The numerical simulations demonstrated good agreement with the PIV experimental results. These findings suggest that it is possible to significantly enhance mixing in microflow systems without mechanical components, solely by exploiting the differences in the magnetic properties between the mixing substances. Traditionally, microreactors have been limited by mixing speeds governed by diffusion. These new results indicate the practical possibility of increasing mixing intensity in a cost-effective and safe manner. Full article
(This article belongs to the Special Issue Advanced Micromixing Technology)
►▼ Show Figures

Figure 1

13 pages, 945 KiB  
Article
Inverse Tesla Valve as Micromixer for Water Purification
by Christos Liosis, George Sofiadis, Evangelos Karvelas, Theodoros Karakasidis and Ioannis Sarris
Micromachines 2024, 15(11), 1371; https://doi.org/10.3390/mi15111371 - 14 Nov 2024
Cited by 1 | Viewed by 822
Abstract
Contaminated water has remained an unsolved problem for decades, particularly when the contamination derived from heavy metals. A possible solution is to mix the contaminated water with magnetic nanoparticles so that an adsorption process can take place. In that frame, Tesla valve micromixer [...] Read more.
Contaminated water has remained an unsolved problem for decades, particularly when the contamination derived from heavy metals. A possible solution is to mix the contaminated water with magnetic nanoparticles so that an adsorption process can take place. In that frame, Tesla valve micromixer and Fe3O4 magnetic nanoparticles were selected to perform simulations for encounter maximum mixing efficiency. These simulations focus on inlet velocities ratios between contaminated water and nanoparticles and inlet rates of nanoparticles. The maximum mixing efficiency was 44% for the inverse double Tesla micromixer found for the combination of Fe3O4 nanoparticles as the inlet rate and with inlet velocity ratios of VpVc=10. Full article
(This article belongs to the Special Issue Advanced Micromixing Technology)
►▼ Show Figures

Figure 1

Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:
 
Displaying articles 1-3
Back to TopTop