Special Issue "Metabolomics in Plant Metabolic Engineering"
A special issue of Metabolites (ISSN 2218-1989).
Deadline for manuscript submissions: closed (28 February 2013)
Metabolomics as a technology in the post-genomics era has rapidly advanced in the past decade for the detection and quantification of steady-state levels of hundreds of metabolites. Developments in instrumentation used for metabolomics and subsequent data analysis pipelines have resulted in numerous applications of metabolomics in the plant sciences. However, in order to determine the carbon and/or nitrogen flow across metabolic pathways and reconstruct metabolic models, sophisticated flux analysis has to be utilized by admission of stable isotope labeled precursors and subsequent quantification of label in each metabolite detectable. This allows a quantification of fluxes through individual pathways; an important necessity for any metabolic engineering approach. Here we aim to collect expert opinions and experiences of how metabolomics has advanced the science of fluxomics to increase our understanding of plasticity of metabolism and improve metabolic engineering attempts in plants as bioreactor organisms.
This special issue “Metabolomics of Plant Metabolic Engineering” of Metabolites will be dedicated to methods used to determine metabolic fluxes, to interpret resulting data and to integrate data with genome-wide models of metabolism. Additionally we aim to present selected examples of metabolic engineering approaches of biotechnologically and pharmaceutically important products in planta.
Dr. Ute Roessner
Manuscript Submission Information
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- metabolic engineering