Special Issue "Metabolomics in Metabolic Engineering"
Deadline for manuscript submissions: closed (15 October 2012).
Interests: biodesign and biological engineering; plant synthetic biology; protein design and engineering; gene-metabolite relationships in medicinal plants; protein expression and production
Stunning advances in synthetic biology have enabled plants and microorganisms to be engineered for the increased production of a wide variety of useful and important metabolites. These breakthroughs have benefited from computational, experimental and technical developments, especially in the areas of genomics and systems biology, and include transcriptomics and metabolomics, as well as modeling efforts to integrate global data on a cellular level. Improved tools for biodesign are increasing our ability to rapidly identify, manipulate and regulate metabolic pathways. Not only are metabolic engineering efforts enhancing our understanding of how interconnected cellular networks can contribute to and affect metabolism and cellular control, but they are finding broad application to pharmaceutical development, nutritional enhancement of plants to improve human health, biomanufacturing and biofuel production. Accordingly, a special issue of Metabolites will focus on multidisciplinary aspects to the design and engineering of diverse biosystems for the production of endogenous or novel metabolites, and highlight computational, experimental or technical approaches for metabolic engineering.
Dr. Edward Eisenstein
- metabolic engineering
- systems biology
- secondary metabolites
- natural products