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Metabolites
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Advances in Metabolism and Nutrition Physiology
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Advances in Metabolism and Nutrition Physiology

A special issue of Metabolites (ISSN 2218-1989). This special issue belongs to the section "Nutrition and Metabolism".

Deadline for manuscript submissions: closed (30 March 2024) | Viewed by 3066

Special Issue Editors

Prof. Dr. Mahmoud Mustafa Ali Abulmeaty

E-Mail Website
Guest Editor
1. Clinical Nutrition Program, Department of Community Health Sciences, College of Applied Medical Sciences, King Saud University, Riyadh, Saudi Arabia
2. Obesity Management & Research Unit, and Medical Physiology Department, Faculty of Medicine, Zagazig University, Zagazig, Egypt
Interests: metabolism; energy expenditure; body composition; nutrition; endocrine
Prof. Dr. Khalid Ali Al-Rubeaan

E-Mail Website
Guest Editor
Professor of Endocrinology, Metabolism, and Diabetes, Director, Research and Scientific Center, Sultan Bin Abdulaziz Humanitarian City, Riyadh, Saudi Arabia
Interests: diabetes; endocrine; metabolism; clinical trials

Special Issue Information

Dear Colleagues,

Metabolism is the machinery system that provides substrates for all cellular chemical reactions to maintain the energy supply for various physiological functions. Studying bioenergetics and metabolic pathways is essential for understanding many biological reactions in both physiological and pathophysiological conditions. Additionally, the metabolome reflects the genomic expression under specific conditions. Metabolomic changes in various health and disease conditions are hot areas of research. Moreover, the study of nutritional physiology involves searching for the mechanisms by which nutrients are extracted from dietary supply and utilized for growth, health maintenance, reproduction, and supporting the metabolic system during various disease conditions. This Special Issue will publish original articles, reviews, systematic reviews, meta-analyses, case studies, and other pieces of work providing answers to many questions in the field of metabolism and nutrition during various health conditions, phases of life, and disease states.  

One of the main aspects of this Special Issue is skeletal muscle metabolism and nutritional support in response to exercise and sports, including how the metabolic pathways adapt to strenuous exercises and regular training, how metabolic pathways are affected by physical inactivity, obesity, and the aging process, and how we can enhance physical performance with novel nutrients or exercise regimens.

Prof. Dr. Mahmoud Mustafa Ali Abulmeaty
Prof. Dr. Khalid Ali Al-Rubeaan
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Metabolites is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Published Papers (2 papers)

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Research

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15 pages, 8154 KiB  
Article
The Effect of Yucca schidigera Extract on Serum Metabolites of Angus Crossbreed Steers with Metabolomics
by Ziqi Deng, Baoyun Wu, Xin Yi, Jinglei Ma, Yue Liu, Luiz Gustavo Nussio, Qingxiang Meng, Zhenming Zhou and Hao Wu
Metabolites 2024, 14(1), 58; https://doi.org/10.3390/metabo14010058 - 15 Jan 2024
Viewed by 1082
Abstract
This study was conducted to explore the potential effect of Yucca schidigera extract (YSE) on the metabolism of beef cattle. Thirty Angus crossbreed steers were selected, with an initial mean body weight of 506.6 ± 33.3 kg, and assigned to two treatments: a [...] Read more.
This study was conducted to explore the potential effect of Yucca schidigera extract (YSE) on the metabolism of beef cattle. Thirty Angus crossbreed steers were selected, with an initial mean body weight of 506.6 ± 33.3 kg, and assigned to two treatments: a diet with no additives (CON group) and a diet supplemented with 1.75 g/kg of YSE (YSE group) (on a dry matter basis). The experiment lasted for 104 days, with 14 days for adaptation. The results showed that adding YSE could significantly improve the average daily gain (ADG) from 1 to 59 d (15.38%) (p = 0.01) and 1 to 90 d (11.38%) (p < 0.01), as well as dry matter digestibility (DMD) (0.84%) (p < 0.05). The contents of alanine aminotransferase, aspartate aminotransferase, and bilirubin and the total antioxidant capacity were increased and blood urea was reduced in the YSE group, compared to the CON group (p < 0.05). Both the glycerophospholipids and bile acids, including phosphocholine, glycerophosphocholine, PC(15:0/18:2(9Z,12Z)), PE(18:0/20:3(5Z,8Z,11Z)), PE(18:3(6Z,9Z,12Z)/P-18:0), LysoPC(15:0), LysoPC(17:0), LysoPC(18:0), LysoPC(20:5(5Z,8Z,11Z,14Z,17Z)), deoxycholic acid, glycocholic acid, and cholic acid, were upregulated by the addition of YSE. In summary, YSE may improve the ADG by increasing the blood total antioxidant capacity and glycerophospholipid synthesis, maintaining steers under a healthy status that is beneficial for growth. Furthermore, YSE may also increase the expression of bile acid synthesis, thereby promoting DMD, which, in turn, offers more nutrients available for growth. Full article
(This article belongs to the Special Issue Advances in Metabolism and Nutrition Physiology)
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Review

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10 pages, 454 KiB  
Review
Association of Selenium Intake and Selenium Concentrations with Risk of Type 2 Diabetes in Adults: A Narrative Review
by Maha Alharithy and Nora Alafif
Metabolites 2023, 13(6), 767; https://doi.org/10.3390/metabo13060767 - 19 Jun 2023
Cited by 1 | Viewed by 1440
Abstract
Several recent studies have suggested selenium (Se) as a potential risk factor for diabetes mellitus (DM); however, the relationship between high Se levels and type 2 diabetes mellitus (T2DM) risk remains unclear. This review article aimed to provide a comprehensive discussion to clarify [...] Read more.
Several recent studies have suggested selenium (Se) as a potential risk factor for diabetes mellitus (DM); however, the relationship between high Se levels and type 2 diabetes mellitus (T2DM) risk remains unclear. This review article aimed to provide a comprehensive discussion to clarify the association between high dietary Se intake and blood Se concentrations and the risk of T2DM among adults. We conducted searches in the PubMed, Science Direct, and Google Scholar databases for the years 2016 to 2022 and evaluated 12 articles from systematic reviews, meta-analyses, cohort studies, and cross-sectional studies. This review found a controversial association between high blood Se concentrations and T2DM risk while demonstrating a positive correlation with DM risk. In contrast, there are conflicting results regarding the association between high dietary Se intake and T2DM risk. Thus, longitudinal studies and randomized controlled trials are needed to better elucidate the link. Full article
(This article belongs to the Special Issue Advances in Metabolism and Nutrition Physiology)
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