Gynecological Surgery: Bridging Research and Clinical Practice

Dear Colleagues,

Minimally invasive gynecologic surgery has transformed pelvic floor reconstruction over the past three decades. Since the introduction of laparoscopic and robotic sacrocolpopexy, surgical management of pelvic organ prolapse has shifted toward techniques that optimize anatomical restoration while reducing morbidity, hospital stay, and recovery time. Advances in mesh technology, nerve-sparing approaches, and refined anatomical understanding have further improved functional outcomes and safety profiles. In parallel, minimally invasive gynecologic oncology has rapidly evolved, enabling precise staging, radical hysterectomy, and lymphadenectomy with reduced complications and faster recovery compared with open surgery. Innovations in imaging, sentinel-node mapping, and robotic platforms continue to redefine standards across benign and oncologic fields, emphasizing individualized, high-value, and patient-centered care.

This Special Issue will provide a comprehensive platform that integrates basic, translational, and clinical research in gynecological surgery. Our goal is to highlight innovative approaches, emerging technologies, and multimodal strategies with the potential to shape future standards of care. By fostering dialogue among researchers, clinicians, and healthcare professionals, we seek to accelerate the translation of scientific knowledge into clinical decision-making and patient management.

We welcome contributions that explore recent advances in genomics, proteomics, tumor microenvironment, immunology, and biomarker discovery, as well as developments in imaging, minimally invasive surgery, and enhanced recovery pathways. Studies investigating novel systemic treatments, including targeted therapies, immunomodulatory strategies, and combination approaches, are particularly encouraged. Additionally, submissions addressing health disparities, survivorship, real-world evidence, digital health tools, and AI-driven predictive models represent an essential component of this Special Issue.

This Special Issue invites high-quality original research articles, systematic reviews, and meta-analyses. Submissions should focus on innovative findings with clear implications for the diagnosis, prognosis, prevention, or treatment of gynecological cancers. Interdisciplinary and collaborative studies that bridge laboratory discoveries with clinical application are especially welcome.

Dr. Vito Andrea Capozzi
Guest Editor

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