Sensitization via Skin Exposure

A special issue of Life (ISSN 2075-1729).

Deadline for manuscript submissions: closed (20 October 2025) | Viewed by 808

Special Issue Editor


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Guest Editor
Department of Medicine, Surgery and Health Sciences, University of Trieste, 34127 Trieste, Italy
Interests: contact dermatitis; patch test; occupational dermatitis; skin absorption of chemicals; skin protection
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Special Issue Information

Dear Colleagues,

Allergic contact dermatitis is one of the most common occupational diseases but can be prevented by reducing contact with sensitizing substances and using adequate personal protective equipment. The early detection of symptoms and identification of the allergens responsible are crucial to resolve symptoms and prevent the disease from becoming chronic. This Special Issue aims to collect data on the epidemiology of allergic contact dermatitis to define best practices for its prevention in occupational settings. Furthermore, it will study the relationship between sensitization via skin exposure and respiratory diseases in occupational groups.

Papers on the epidemiology of contact dermatitis, patch test sensitization to various allergens, and follow-up results after preventive interventions are welcomed, especially those analyzing gender and occupational groups.

We look forward to receiving your valuable contributions.

Prof. Dr. Francesca Filon
Guest Editor

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Keywords

  • contact dermatitis
  • patch test
  • epidemiology
  • occupation
  • prevention

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Published Papers (1 paper)

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Research

10 pages, 230 KB  
Article
Sensitization to Disperse Blue Dye 124 in Triveneto Region from 1997 to 2021 and Its Potential Occupational Role
by Nicholas Zampa, Serena Romanelli, Anna Belloni Fortina, Erika Giulioni, Luca Cegolon and Francesca Larese Filon
Life 2025, 15(11), 1711; https://doi.org/10.3390/life15111711 - 5 Nov 2025
Viewed by 524
Abstract
Objective: To investigate the sensitization to the dispersal of blue 124, a synthetic dye used in textile applications. The chemical properties of this dye allow it to migrate from fabrics to the skin, posing a risk for sensitization and allergic reactions. Materials [...] Read more.
Objective: To investigate the sensitization to the dispersal of blue 124, a synthetic dye used in textile applications. The chemical properties of this dye allow it to migrate from fabrics to the skin, posing a risk for sensitization and allergic reactions. Materials and Methods: A retrospective analysis of 30,629 consecutive patch test data from 1997 to 2021 in the Triveneto region (Italy) was performed using disperse blue 124 1% in petrolatum. Data were analyzed to assess trends in sensitization rates across different demographics and occupational groups. Results: The prevalence of sensitization to disperse blue 124 was 2.5% (n. 780 patients) and declined over the considered period, reaching a prevalence of approximately 1.5–1.9% in recent years. Sensitization was slightly higher in women (2.7%) compared to men (2.3%, p = 0.053), and in 36–65-year-old individuals (p < 0.05). Painters and textile workers presented a mild increase in sensitization, without reaching the statistical significance. Discussion: Disperse blue 124 sensitization declined significantly over the considered period, probably as result of the reduced use of this dye in textiles available on the Italian market. Its occupational role is limited. Conclusions: Contact dermatitis associated with disperse blue 124 declined over the considered period, but it is still above 1%, indicating the need for monitoring. Full article
(This article belongs to the Special Issue Sensitization via Skin Exposure)
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