From Animal Models to Clinical Innovations: Translating Research into Medicine
A special issue of Life (ISSN 2075-1729). This special issue belongs to the section "Animal Science".
Deadline for manuscript submissions: 22 May 2026 | Viewed by 814
Special Issue Editors
Interests: animal experimentation; comparative anatomy and physiology; animal behavior and psychology; animal-based product testing; implantology
Interests: cardiovascular diseases; metabolic diseases; diabetes mellitus; antioxidants
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
This section is devoted to the promotion and dissemination of scientific findings derived from animal research, encompassing a wide array of organisms ranging from insects and invertebrates to higher vertebrates, and always conducted in accordance with current ethical and legal frameworks. Its primary objective is to provide a rigorous platform for the publication of original experimental studies and comprehensive bibliographic reviews that critically evaluate the relevance, validity, and appropriateness of animal use in biomedical investigations. Emphasis is placed on the translational value of such studies, particularly with regard to their contribution to bridging fundamental research with clinical practice.
An essential aspect addressed in this section concerns the recognition of interspecies differences, which often represent a limiting factor in extrapolating preclinical results to human or veterinary medicine. Advances in genetic engineering, including the development of transgenic and genome-edited animal models, are highlighted as significant tools to mitigate these discrepancies and enhance predictive accuracy. Furthermore, this section welcomes contributions that examine the ethical, societal, and regulatory dimensions of animal experimentation, acknowledging the increasing public scrutiny of research practices and the demand for greater transparency and refinement, reduction, and replacement strategies.
Finally, the section encourages submissions exploring the application of animal models across a broad range of scientific domains in both human and veterinary medicine. These include, but are not limited to, comparative morphology, surgery, parasitic diseases, biochemistry, pharmacology, oncology, cardiovascular and metabolic diseases, neuroscience, infectious diseases, and other specialized research fields, where animal experimentation continues to provide indispensable insights into pathophysiology, therapeutic innovation, and translational outcomes.
Prof. Dr. Mihaela-Claudia Spataru
Prof. Dr. Manuela Ciocoiu
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Life is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- animal models
- animal research
- biomedical research
- ethics of animal experimentation
- experimentation on animals
- interspecies differences
- translational medicine
- human clinical medicine
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