Traumatic Brain Injury: Epidemiology, Diagnosis, Treatment and Biomarkers

Dear Colleagues,

Traumatic brain injury is a major cause of morbidity and mortality throughout the world. Among persons younger than 45 years old, injury is the major cause of death, and TBI is the major cause of injury.

That said, the epidemiology of human traumatic brain injury is something of a moving target. It is unknown what proportion of those experiencing a TBI—of any severity—present for medical assessment. Even in industrialized countries with reasonably good methods of data gathering, no central registry can expect to capture more cases than those coded appropriately and systematically surveyed. The best one can do is to enumerate such known cases.

The epidemiology of TBI also varies by subpopulations. Infantile, pediatric, teen, adult, and elderly cases occur due to different circumstances and may have different outcomes. Sex, race, socioeconomic level, and other factors influence the incidence of both initial and recurrent injuries.

The goal of this Special Issue is to compile expert reviews regarding the epidemiology of TBI. Insofar as possible, specific data will be examined with respect to the differing epidemiology in important subpopulations. A secondary goal is to identify predictors of outcome, for instance, clinical and biomarker factors that appear to anticipate the patient’s long-term prognosis.

Dr. Jeff Victoroff
Dr. Alfredo Conti
Guest Editors

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