Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
6.0
3.4
Journals
Life
Special Issues
Treatment and Prognosis of Thoracic Diseases
share announcement

Treatment and Prognosis of Thoracic Diseases

A special issue of Life (ISSN 2075-1729). This special issue belongs to the section "Medical Research".

Deadline for manuscript submissions: 30 July 2026 | Viewed by 1676

Special Issue Editors

Dr. Alessandro Gonfiotti

E-Mail Website
Guest Editor
1. Thoracic Surgery Unit, Careggi University Hospital, 50134 Florence, Italy
2. Department of Experimental and Clinical Medicine, University of Florence, 50134 Florence, Italy
Interests: cardiothoracic surgery; radio-guided thoracic surgery; mediastinal tumors surgery; tracheal surgery; minimally invasive thoracic surgery; surgery of mesothelioma; lung cancer staging and treatment; video-assisted sympathectomy for essential hyperhidrosis; surgery of bullous emphysema; lung volume reduction surgery; video-assisted thoracic surgery
Special Issues, Collections and Topics in MDPI journals
Dr. Alice Ravasin

E-Mail Website
Guest Editor Assistant
Thoracic Surgery Unit, Careggi University Hospital, 50134 Florence, Italy
Interests: lung cancer; video-assisted thoracic surgery; chest wall surgery; robotic surgery; mediastinal tumor

Special Issue Information

Dear Colleagues,

Thoracic diseases encompass a wide spectrum of benign and malignant conditions affecting the lungs, pleura, mediastinum, diaphragm, and chest wall, including lung cancer, mesothelioma, interstitial lung diseases, pleural effusions, thoracic infections, and mediastinal tumors, among others.

Clinical presentations vary significantly, ranging from incidental findings on imaging to acute, life-threatening emergencies. In recent years, major advances have occurred in diagnostic modalities, including high-resolution imaging, molecular profiling, and minimally invasive biopsy techniques. Concurrently, treatment strategies have evolved through the integration of targeted therapies, immunotherapy, and precision surgery.

This Special Issue aims to highlight contemporary approaches and emerging trends in the management of thoracic diseases, with a particular focus on individualized treatment planning and prognostic assessment. Contributions from multidisciplinary teams—including pulmonologists, thoracic surgeons, radiologists, oncologists, and pathologists—are essential to provide a comprehensive perspective on current clinical practice and research.

Dr. Alessandro Gonfiotti
Guest Editor

Dr. Alice Ravasin
Guest Editor Assistant

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Life is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • thoracic malignancies
  • lung cancer management 
  • targeted therapy 
  • immunotherapy 
  • molecular diagnostics 
  • multidisciplinary care 
  • personalized treatment

Benefits of Publishing in a Special Issue

  • Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
  • Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
  • Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
  • External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
  • Reprint: MDPI Books provides the opportunity to republish successful Special Issues in book format, both online and in print.

Further information on MDPI's Special Issue policies can be found here.

Published Papers (1 paper)

Order results
Result details
Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:

Review

27 pages, 649 KB  
Review
Pulmonary Manifestations of Inborn Errors of Immunity: Diagnostic and Therapeutic Insights
by Katarzyna Napiorkowska-Baran, Szczepan Cofta, Paweł Treichel, Marta Tykwinska, Kinga Lis, Aleksandra Matyja-Bednarczyk, Bartłomiej Szymczak, Maciej Szota, Jozef Slawatycki, Michal Kulakowski and Zbigniew Bartuzi
Life 2025, 15(12), 1838; https://doi.org/10.3390/life15121838 - 29 Nov 2025
Viewed by 1416
Abstract
Background: Inborn errors of immunity (IEIs) are a heterogeneous group of genetically determined disorders that lead to immune dysfunction, recurrent infections, and organ-specific complications. The lungs are among the most commonly affected organs, with both infectious and noninfectious manifestations that significantly contribute to [...] Read more.
Background: Inborn errors of immunity (IEIs) are a heterogeneous group of genetically determined disorders that lead to immune dysfunction, recurrent infections, and organ-specific complications. The lungs are among the most commonly affected organs, with both infectious and noninfectious manifestations that significantly contribute to morbidity and mortality. This study aimed to provide a comprehensive overview of pulmonary manifestations in IEI, with emphasis on pathophysiological mechanisms, diagnostic approaches, and therapeutic strategies. Methods: A narrative review and synthesis of current literature and clinical guidelines were conducted, focusing on pulmonary involvement in IEI as classified by the International Union of Immunological Societies (IUIS). The analysis included data on infectious and noninfectious complications, imaging findings, immunological assessments, and management strategies, supported by clinical evidence and expert consensus. Results: Pulmonary manifestations in IEI encompass a wide spectrum of conditions. Infectious complications include recurrent bacterial pneumonias, bronchitis, and opportunistic infections, frequently resulting in irreversible lung damage such as bronchiectasis. Noninfectious complications, including granulomatous–lymphocytic interstitial lung disease (GLILD) and interstitial lung disease (ILD), are common in disorders such as common variable immunodeficiency (CVID) and X-linked agammaglobulinemia (XLA). Early diagnosis using high-resolution computed tomography (HRCT) and immunological testing, combined with the timely initiation of immunoglobulin replacement therapy and anti-biotic prophylaxis, significantly improves prognosis. Conclusions: Pulmonary complications are key clinical indicators of IEI and often precede systemic manifestations. Early, integrated, and interdisciplinary diagnostic and therapeutic management are crucial for preventing irreversible lung damage and improving patient outcomes. Regular monitoring and individualized therapy, including immunoglobulin replacement, targeted immunosuppression, and vaccination, are the cornerstones of effective long-term care in IEI. Full article
(This article belongs to the Special Issue Treatment and Prognosis of Thoracic Diseases)
►▼ Show Figures

Figure 1

Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:
 
Displaying articles 1-1
Back to TopTop